{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0","upperLimit":"0","value":"0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"2"}],"units":"Participants"}],"title":"Symptoms (M3)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"-1","upperLimit":"11","value":"5"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"2"}],"units":"Participants"}],"title":"Past week (M3)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"-3","upperLimit":"0","value":"-1.5"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"2"}],"units":"Participants"}],"title":"Global health status (M3)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"-1","upperLimit":"3","value":"1"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"7"}],"units":"Participants"}],"title":"Symptoms (M6)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"-4","upperLimit":"9","value":"6"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"7"}],"units":"Participants"}],"title":"Past week (M6)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"-7","upperLimit":"0","value":"-1"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"7"}],"units":"Participants"}],"title":"Global health status (M6)"}],"denoms":[{"counts":[{"groupId":"OG000","value":"8"}],"units":"Participants"}],"description":"Median change in symptom scores. Scale is the EORTC QLQ-C30. There are three domains: symptom scale (score range 7-14); past week (score range 21-82); and global health status (score range 2-14). Higher or increasing scores mean worse outcomes; lower or decreasing scores mean better outcomes.","dispersionType":"Full Range","groups":[{"description":"Subject will take tadalafil in combination with with Lenalidomide and dexamethasone (Rd) or Clarithromycin/Lenalidomide/ dexamethasone (BiRd)\n\nTadalafil: Tadalafil will be administered at a dose of 20 mg orally daily starting with day 1 of the first cycle. Each cycle will last for 28 days\n\nLenalidomide: Lenalidomide will be administered as it was prior to study entry.\n\nDexamethasone: Dexamethasone will be administered as it was prior to study entry.\n\nClarithromycin: Clarithromycin will be administered as it was prior to study entry.","id":"OG000","title":"Tadalafil"}],"paramType":"MEDIAN","populationDescription":"Two participants returned the Month 3 survey and seven participants returned the Month 6 survey (there is some overlap). The remaining participants cannot be analyzed as there is no follow-up data.","reportingStatus":"POSTED","timeFrame":"3 months (M3) and 6 months (M6)","title":"Quality of Life Scores","type":"SECONDARY","unitOfMeasure":"change in score on a scale"}