{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0","upperLimit":"0","value":"0"}]}],"title":"-0.5 h (Day 0)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0","upperLimit":"14.5","value":"0.91"}]}],"title":"-0.5 h (Day 28)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0","upperLimit":"14.10","value":"3.83"}]}],"title":"0.5 h (Day 0)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0","upperLimit":"12.90","value":"1.58"}]}],"title":"0.5 h (Day 28)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0","upperLimit":"18.8","value":"11.04"}]}],"title":"1 h (Day 0)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0","upperLimit":"14.40","value":"1.55"}]}],"title":"1 h (Day 28)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0","upperLimit":"168","value":"72.73"}]}],"title":"2 h (Day 0)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0.00","upperLimit":"16.60","value":"1.96"}]}],"title":"2 h (Day 28)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0.00","upperLimit":"160.00","value":"84.35"}]}],"title":"3 h (Day 0)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0.00","upperLimit":"29.20","value":"2.48"}]}],"title":"3 h (Day 28)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0.00","upperLimit":"67.50","value":"28.29"}]}],"title":"4 h (Day 0)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0.00","upperLimit":"37.70","value":"3.12"}]}],"title":"4 h (Day 28)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0.00","upperLimit":"0.00","value":"0.00"}]}],"title":"6 h (Day 0)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0.00","upperLimit":"39.50","value":"7.33"}]}],"title":"6 h (Day 28)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0.00","upperLimit":"0.00","value":"0.00"}]}],"title":"8 h (Day 0)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0.00","upperLimit":"43.70","value":"10.23"}]}],"title":"8 h (Day 28)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0.00","upperLimit":"0.00","value":"0.00"}]}],"title":"24 h (Day 0)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0.00","upperLimit":"0.00","value":"0.00"}]}],"title":"24 h (Day 28)"}],"denoms":[{"counts":[{"groupId":"OG000","value":"16"}],"units":"Participants"}],"description":"Estrogens were analyzed using a highly sensitive gas chromatography-mass spectrometry (GC/MS) method. The lower limits of quantitation (LLOQ) were 10.00 pg/ml for E3, 1.The coefficient of variation (CV, intra-assay variation) was 2.0 % for E3 (calibration range (CR) 10.00-500.00 pg/).\n\nThe lower limits of quantitation (LLOQ) were 1.00 pg/ml for E2, and 2.00 pg/ml for E1.The coefficient of variation (CV, intra-assay variation) was 4.2 % for E2 (CR 1.00-150.00 pg/ml), and 3.4 % for E1 (CR 2.00-300.00 pg/ml).","dispersionType":"Full Range","groups":[{"description":"Gynoflor: Vaginal tablet with lyophilised lactobacilli and 0.03 mg estriol; once daily for 28 days then 3 times per week for 8 weeks;","id":"OG000","title":"Gynoflor"}],"paramType":"MEAN","reportingStatus":"POSTED","timeFrame":"-0.5, 0.5, 1, 2, 3, 4, 6, 8, 24 hours on days 0 and 28","title":"Serum Concentrations of Estriol (E3)","type":"PRIMARY","unitOfMeasure":"pg/ml"}