{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"93.85","upperLimit":"95.71","value":"94.78"},{"groupId":"OG001","lowerLimit":"92.93","upperLimit":"94.92","value":"93.93"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"1544"},{"groupId":"OG001","value":"1522"}],"units":"Participants"}],"title":"6 Years"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"91.66","upperLimit":"93.82","value":"92.74"},{"groupId":"OG001","lowerLimit":"90.83","upperLimit":"93.09","value":"91.96"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"1827"},{"groupId":"OG001","value":"1834"}],"units":"Participants"}],"title":"8 Years"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"90.38","upperLimit":"92.71","value":"91.55"},{"groupId":"OG001","lowerLimit":"88.53","upperLimit":"91.06","value":"89.79"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"1798"},{"groupId":"OG001","value":"1742"}],"units":"Participants"}],"title":"10 Years"}],"denoms":[{"counts":[{"groupId":"OG000","value":"2400"},{"groupId":"OG001","value":"2404"}],"units":"Participants"}],"description":"The Kaplan-Meier approach was used to estimate the percentage of participants who were alive at 6, 8, and 10 years. Participants who were alive (including lost to follow-up) at the time of the analysis were censored at the date when they were last known to be alive.","dispersionType":"95% Confidence Interval","groups":[{"description":"Participants received pertuzumab (840 mg loading dose, then 420 mg) and trastuzumab (8 mg/kg loading dose, then 6 mg/kg) IV Q3W for 1 year (maximum 18 cycles) in combination with 1 of the following IV chemotherapy regimen (anthracycline-based or nonanthracycline-based) per Investigator's choice: 1) 3-4 cycles (Q3W) of 5-fluorouracil 500-600 mg/m\\^2 + epirubicin 90-120 mg/m\\^2 or doxorubicin 50 mg/m\\^2 + cyclophosphamide 500-600 mg/m\\^2 followed by either 3-4 cycles of docetaxel Q3W (100 mg/m\\^2 for 3 cycles, 75 mg/m\\^2 in first cycle and 100 mg/m\\^2 in subsequent cycles, or 75 mg/m\\^2 for 4 cycles) or 12 cycles of paclitaxel 80 mg/m\\^2 QW; 2) 4 cycles (Q3W) of doxorubicin 60 mg/m\\^2 or epirubicin 90-120 mg/m\\^2 + cyclophosphamide 500-600 mg/m\\^2 followed by either 3-4 cycles of docetaxel Q3W or 12 cycles of paclitaxel QW (as described in Option 1); 3) 6 cycles (Q3W) of docetaxel 75 mg/m\\^2 + carboplatin area under the curve (AUC) 6 (up to 900 mg).","id":"OG000","title":"Pertuzumab + Trastuzumab + Chemotherapy"},{"description":"Participants received placebo matched to pertuzumab IV Q3W and trastuzumab (8 mg/kg loading dose, then 6 mg/kg) IV Q3W for 1 year (maximum 18 cycles) in combination with 1 of the following IV chemotherapy regimen (anthracycline-based or nonanthracycline-based) per Investigator's choice: 1) 3-4 cycles (Q3W) of 5-fluorouracil 500-600 mg/m\\^2 + epirubicin 90-120 mg/m\\^2 or doxorubicin 50 mg/m\\^2 + cyclophosphamide 500-600 mg/m\\^2 followed by either 3-4 cycles of docetaxel Q3W (100 mg/m\\^2 for 3 cycles, 75 mg/m\\^2 in first cycle and 100 mg/m\\^2 in subsequent cycles, or 75 mg/m\\^2 for 4 cycles) or 12 cycles of paclitaxel 80 mg/m\\^2 QW; 2) 4 cycles (Q3W) of doxorubicin 60 mg/m\\^2 or epirubicin 90-120 mg/m\\^2 + cyclophosphamide 500-600 mg/m\\^2 followed by either 3-4 cycles of docetaxel Q3W or 12 cycles of paclitaxel QW (as described in Option 1); 3) 6 cycles (Q3W) of docetaxel 75 mg/m\\^2 + carboplatin AUC 6 (up to 900 mg).","id":"OG001","title":"Placebo + Trastuzumab + Chemotherapy"}],"paramType":"NUMBER","populationDescription":"The overall number of participants analyzed is the ITT population. The number analyzed is the number of participants remaining at risk for death at at the time of analysis for each timepoint.","reportingStatus":"POSTED","timeFrame":"6, 8, and 10 years","title":"Kaplan-Meier Estimate of the Percentage of Participants Who Were Alive at 6, 8, and 10 Years","type":"SECONDARY","unitOfMeasure":"Estimate of percentage of participants"}