{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"37"},{"groupId":"OG001","value":"41"}],"title":"No Nausea"},{"measurements":[{"groupId":"OG000","value":"17"},{"groupId":"OG001","value":"8"}],"title":"Mild Nausea"},{"measurements":[{"groupId":"OG000","value":"16"},{"groupId":"OG001","value":"19"}],"title":"Moderate Nausea"},{"measurements":[{"groupId":"OG000","value":"12"},{"groupId":"OG001","value":"12"}],"title":"Severe Nausea"}],"denoms":[{"counts":[{"groupId":"OG000","value":"82"},{"groupId":"OG001","value":"80"}],"units":"Participants"}],"title":"Day 1"},{"categories":[{"measurements":[{"groupId":"OG000","value":"17"},{"groupId":"OG001","value":"15"}],"title":"No Nausea"},{"measurements":[{"groupId":"OG000","value":"23"},{"groupId":"OG001","value":"27"}],"title":"Mild Nausea"},{"measurements":[{"groupId":"OG000","value":"24"},{"groupId":"OG001","value":"20"}],"title":"Moderate Nausea"},{"measurements":[{"groupId":"OG000","value":"16"},{"groupId":"OG001","value":"18"}],"title":"Severe Nausea"}],"denoms":[{"counts":[{"groupId":"OG000","value":"80"},{"groupId":"OG001","value":"80"}],"units":"Participants"}],"title":"Day 2"},{"categories":[{"measurements":[{"groupId":"OG000","value":"13"},{"groupId":"OG001","value":"16"}],"title":"No Nausea"},{"measurements":[{"groupId":"OG000","value":"19"},{"groupId":"OG001","value":"17"}],"title":"Mild Nausea"},{"measurements":[{"groupId":"OG000","value":"18"},{"groupId":"OG001","value":"21"}],"title":"Moderate Nausea"},{"measurements":[{"groupId":"OG000","value":"20"},{"groupId":"OG001","value":"10"}],"title":"Severe Nausea"}],"denoms":[{"counts":[{"groupId":"OG000","value":"70"},{"groupId":"OG001","value":"64"}],"units":"Participants"}],"title":"Day 3"},{"categories":[{"measurements":[{"groupId":"OG000","value":"13"},{"groupId":"OG001","value":"16"}],"title":"No Nausea"},{"measurements":[{"groupId":"OG000","value":"10"},{"groupId":"OG001","value":"12"}],"title":"Mild Nausea"},{"measurements":[{"groupId":"OG000","value":"11"},{"groupId":"OG001","value":"10"}],"title":"Moderate Nausea"},{"measurements":[{"groupId":"OG000","value":"16"},{"groupId":"OG001","value":"5"}],"title":"Severe Nausea"}],"denoms":[{"counts":[{"groupId":"OG000","value":"50"},{"groupId":"OG001","value":"43"}],"units":"Participants"}],"title":"Days 4-7"}],"denoms":[{"counts":[{"groupId":"OG000","value":"83"},{"groupId":"OG001","value":"82"}],"units":"Participants"}],"description":"CIN = Chemotherapy-Induced Nausea. The acute phase began with administration of the first chemotherapy dose of a chemotherapy block and continued until 24 hours after administration of the last chemotherapy dose of the block. Acute Phase - bands will be worn on each day of the chemotherapy course and for 24 hours after the last chemotherapy dose. Nausea severity during the acute phase of chemotherapy is defined as the maximum PeNAT (Pediatric Nausea Assessment Tool) score observed during each 24 hour period. The possible scores for the pediatric nausea assessment tool are no nausea, mild nausea, moderate nausea, severe nausea. Only patients who contributed at least 1 PeNAT score during the acute phase were included. The duration of the acute phase varied with chemotherapy regimen, according to study design.","groups":[{"description":"Patients wear Sea-Band acupressure wristbands on each wrist beginning approximately 30 minutes prior to the first cisplatin-containing chemotherapy course and continually for 24 hours after the last chemotherapy dose (acute phase), and for a maximum of 7 days or until the next chemotherapy course starts (delayed phase). Patients are allowed to take bands off intermittently (up to 4 times a day, for no more than 15 minutes each time) to relieve pressure or to bathe. Patients also receive standard of care anti-emetic prophylaxis comprising granisetron, ondansetron, or dexamethasone during chemotherapy according to institutional or physician preference.\n\nReal Acupressure Band: Acupressure wristband","id":"OG000","title":"Arm I- Real Acupressure Bands"},{"description":"Patients wear placebo wristbands on each wrist and receive standard of care anti-emetic prophylaxis during chemotherapy as patients in arm I.\n\nPlacebo Acupressure Band: Sham wristband","id":"OG001","title":"Arm II- Placebo Acupressure Bands"}],"paramType":"COUNT_OF_PARTICIPANTS","populationDescription":"The overall number of patients analyzed is 83 for Arm I and 82 for Arm II. Patients analyzed include the total number of patients that reported at least 1 PeNAT (Pediatric Nausea Assessment Tool) score on that day. The duration of the acute phase varied with chemotherapy regimen, according to study design. The number of patients receiving chemotherapy for longer than 3 days diminished each day, so days 4-7 were collapsed and considered a single day.","reportingStatus":"POSTED","timeFrame":"Each day of Chemotherapy course. Maximum of 7 days","title":"Efficacy of Treatment on CIN During Acute Phase of Chemotherapy","type":"PRIMARY","unitOfMeasure":"Participants"}