{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"3.58","upperLimit":"7.62","value":"6.47"},{"comment":"Insufficient participants reached the median percentile to calculate the upper limits of confidence interval.","groupId":"OG001","lowerLimit":"2.14","upperLimit":"NA","value":"4.17"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"34"},{"groupId":"OG001","value":"12"}],"units":"Participants"}],"description":"Duration of response is defined as the time from the date of initial documentation of a response (CR or PR) to the date of first documented evidence of progressive disease (or relapse for participants who experience CR during the study) or death.\n\nIndependent Data Monitoring Committee performed ongoing safety monitoring and conducted the interim analysis after 189 death events and 329 PFS events were observed.","dispersionType":"95% Confidence Interval","groups":[{"description":"Trabectedin at a dose of 1.5 milligram per meter square (mg/m\\^2) was given as an intravenous (IV) infusion over 24-hour every 3 weeks on Day 1 of every cycle (21 days) until disease progression. Dexamethasone 20 mg IV was also administered within 30 minutes before start of each trabectedin infusion.","id":"OG000","title":"Trabectedin"},{"description":"Dacarbazine at a dose of 1 gram per meter square (mg/m\\^2) was given as an intravenous (IV) infusion over 20-120 minutes every 3 weeks on Day 1 of every cycle (21 days) until disease progression. Dexamethasone 20 mg IV was also administered within 30 minutes before start of each dacarbazine infusion.","id":"OG001","title":"Dacarbazine"}],"paramType":"MEDIAN","populationDescription":"Analysis population included all the randomized participants up to interim analysis cut-off date (16 September 2013). \"N\" (number of participants analyzed) signifies the participants evaluable for this measure.","reportingStatus":"POSTED","timeFrame":"approximately 2 years 4 months (From Study start date [27 May 2011] up to interim analysis data cut-off [16 September 2013])","title":"Duration of Response","type":"SECONDARY","unitOfMeasure":"Months"}