{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"6.9","upperLimit":"13.5","value":"9.9"},{"groupId":"OG001","lowerLimit":"3.6","upperLimit":"11.8","value":"6.9"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"345"},{"groupId":"OG001","value":"173"}],"units":"Participants"}],"description":"The objective response rate (ORR) is defined as the percentage of participants who achieved a Complete response (CR) or partial response (PR) as best responses. according to Response Evaluation Criteria in Solid Tumors, Version 1.1 (RECIST). CR defined as disappearance of all target lesions. Any pathological lymph nodes must have reduction in short axis to less than 10 millimeter (mm). PR defined as at least 30 percent (%) decrease in sum of the diameters of the target lesions taking as reference the Baseline sum diameters. Confirmed responses are those that persist on repeat imaging study for at least 4 weeks after initial documentation of response. Independent Data Monitoring Committee performed ongoing safety monitoring and conducted the interim analysis after 189 death events and 329 PFS events were observed.","dispersionType":"95% Confidence Interval","groups":[{"description":"Trabectedin at a dose of 1.5 milligram per meter square (mg/m\\^2) was given as an intravenous (IV) infusion over 24-hour every 3 weeks on Day 1 of every cycle (21 days) until disease progression. Dexamethasone 20 mg IV was also administered within 30 minutes before start of each trabectedin infusion.","id":"OG000","title":"Trabectedin"},{"description":"Dacarbazine at a dose of 1 gram per meter square (mg/m\\^2) was given as an intravenous (IV) infusion over 20-120 minutes every 3 weeks on Day 1 of every cycle (21 days) until disease progression. Dexamethasone 20 mg IV was also administered within 30 minutes before start of each dacarbazine infusion.","id":"OG001","title":"Dacarbazine"}],"paramType":"NUMBER","populationDescription":"Analysis population included all the randomized participants up to interim analysis cut-off date (16 September 2013). \"N\" (number of participants analyzed) signifies the participants evaluable for this measure.","reportingStatus":"POSTED","timeFrame":"approximately 2 years 4 months (From Study start date [27 May 2011] up to interim analysis data cut-off [16 September 2013])","title":"Objective Response Rate","type":"SECONDARY","unitOfMeasure":"Percentage of Participants"}