{"analyses":[{"ciLowerLimit":"1.16","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"1.87","estimateComment":"Cochran Mantel Haenszel (CMH) test including treatment, age class and region as strata. All missing data were to be imputed as treatment failures.","groupDescription":"The null hypothesis was rejected if the 2 sided p value from the Cochran Mantel Haenszel test was less than or equal to 0.050 and in the right direction i.e., the Odds Ratio (OR) was in favor of netupitant/palonosetron. Power was 90%.","groupIds":["OG000","OG001"],"nonInferiorityType":"SUPERIORITY_OR_OTHER","pValue":"0.001","pValueComment":"If superiority of netupitant/palonosetron was established for the CR delayed, CR acute and then CR overall at cycle 1 were to be tested according to a hierarchical procedure;no adjustment for multiplicity was needed.The a priori threshold was 0.050","paramType":"Odds Ratio (OR)","paramValue":"1.48","statisticalMethod":"Cochran-Mantel-Haenszel","testedNonInferiority":false}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"73.7","upperLimit":"79.9","value":"76.9"},{"groupId":"OG001","lowerLimit":"66.1","upperLimit":"72.8","value":"69.5"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"724"},{"groupId":"OG001","value":"725"}],"units":"Participants"}],"dispersionType":"95% Confidence Interval","groups":[{"description":"Oral netupitant/palonosetron (300 mg/0.50 mg) hard capsule with oral dexamethasone, both given on Day 1, prior to each scheduled chemotherapy cycle\n\nNetupitant and Palonosetron\n\nDexamethasone","id":"OG000","title":"Netupitant and Palonosetron Plus Dexamethasone"},{"description":"Oral palonosetron 0.50 mg (Aloxi) with oral dexamethasone both given on Day 1, prior to each scheduled chemotherapy cycle\n\nPalonosetron\n\nDexamethasone","id":"OG001","title":"Palonosetron Plus Dexamethasone"}],"paramType":"NUMBER","populationDescription":"FAS","reportingStatus":"POSTED","timeFrame":"25-120 hours","title":"Percentage of Patients With Complete Response (CR) Defined as no Emesis, no Rescue Medication, at Cycle 1","type":"PRIMARY","unitOfMeasure":"percentage of responders"}