{"analyses":[{"groupIds":["OG000"],"nonInferiorityType":"OTHER","pValue":"0.0075","statisticalMethod":"Wilcoxon's rank sum test"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"3","upperLimit":"13","value":"5"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"5"}],"units":"Participants"}],"title":"Patients with SUV 1.4 or greater"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"8","upperLimit":"22","value":"15"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"15"}],"units":"Participants"}],"title":"Patients with SUV less than 1.4"}],"denoms":[{"counts":[{"groupId":"OG000","value":"20"}],"units":"Participants"}],"description":"18F-FLT imaging was performed serially on patients post transplant to identify the level of uptake of 18F-FLT at a day +5 to +12 scan and the day at which neutrophils recover to \\>500 (i.e., subclinical bone-marrow recovery within 5 days of Bone Marrow Transplantation (BMT infusion)). On each image for each patient, the region of interest was drawn within each thoracic medullary space (n=12), generating the SUV for each space. The mean of these was calculated for each scan. The analysis was the median of the means of the SUV of the thorax values of the day 5-12 scan (averaged the SUV of the thorax for each patient and then took the medians of these).","dispersionType":"Full Range","groups":[{"description":"Patients receiving first allogeneic bone marrow transplant on this study.","id":"OG000","title":"Transplant Recipient"}],"paramType":"MEDIAN","populationDescription":"The pre-specified cohort for this endpoint was 23 first BMT recipients. Only 20 of 23 were evaluable due to inability to obtain the early scan (1) or early relapse (2). As pre-specified in the protocol, all 20 patients were analyzed together as the intention was to look at the imaging modality itself and not any effect of leuprolide.","reportingStatus":"POSTED","timeFrame":"18F FLT scan done between days +5 to +12 and then time from that scan to engraftment measured","title":"Time to Engraftment in First Transplant Recipients Only With Median Thoracic Spine Standardized Uptake Values (SUV) of 1.4 or Greater Than Those Patients With SUV's Less Than 1.4","type":"PRIMARY","unitOfMeasure":"Days"}