{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"9.2","value":"11.4"}]}],"title":"Average absorbed dose to the marrow"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"6.8","value":"17.2"}]}],"title":"Average absorbed dose to the liver"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"5.7","value":"3.1"}]}],"title":"Average abosorbed dose total body"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"43","value":"70"}]}],"title":"Average absorbed dose to the spleen"}],"denoms":[{"counts":[{"groupId":"OG000","value":"15"}],"units":"Participants"}],"description":"The amount of energy absorbed per unit weight of the organ or tissue is called absorbed dose and is expressed in units of gray (Gy). One gray dose is equivalent to one joule radiation energy absorbed per kilogram of organ or tissue weight.","dispersionType":"Standard Deviation","groups":[{"description":"PREPARATIVE REGIMEN: Patients receive 90Y-BC8 via central line on approximately day -12, fludarabine phosphate IV over 30 minutes on days -4 to -2, and 2 Gy TBI on day 0.\n\nTRANSPLANTATION: Patients undergo allogeneic PBSC or bone marrow transplant on day 0.\n\nGVHD PROPHYLAXIS: Patients receive mycophenolate mofetil PO or IV every 12 hours on days 0-27 (for patients with related donors) or every 8 hours on days 0-40 with taper to day 96 (for patients with unrelated donors). Patients also receive cyclosporine PO or IV every 12 hours on days -3 to 56 (for patients with related donors) or 100 (for patients with unrelated donors) with taper to day 180.\n\nAllogeneic Bone Marrow Transplantation: Undergo allogeneic bone marrow transplant\n\nAllogeneic Hematopoietic Stem Cell Transplantation: Undergo allogeneic PBSC or bone marrow transplant\n\nCyclosporine: Given PO or IV\n\nFludarabine Phosphate: Given IV\n\nIndium In 111 Anti-CD45 Monoclonal Antibody BC8: Given IV (dosimetric dose)","id":"OG000","title":"Treatment (90Y-BC8, Allogeneic PBSC or Bone Marrow Transplant)"}],"paramType":"MEAN","populationDescription":"All study participants who completed the study regimen.","reportingStatus":"POSTED","timeFrame":"Approximately day -20 to day -12 prior to transplant","title":"Estimation of Absorbed Radiation Doses to Normal Organs, Marrow and Tumor","type":"SECONDARY","unitOfMeasure":"Gy"}