{"analyses":[{"ciLowerLimit":"-0.13","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"0.24","groupDescription":"Difference in the measurements for touch by the fingertip","groupIds":["OG000","OG001"],"nonInferiorityType":"SUPERIORITY","pValue":"0.54","paramType":"Mean Difference (Final Values)","paramValue":"0.06","statisticalMethod":"Wilcoxon (Mann-Whitney)"},{"ciLowerLimit":"-0.13","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"0.23","groupDescription":"Difference in the measurements for touch by the palm","groupIds":["OG000","OG001"],"nonInferiorityType":"OTHER","pValue":"0.60","paramType":"Mean Difference (Final Values)","paramValue":"0.05","statisticalMethod":"Wilcoxon (Mann-Whitney)"},{"ciLowerLimit":"-0.40","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"0.15","groupDescription":"Difference in the measurements for touch by the forearm","groupIds":["OG000","OG001"],"nonInferiorityType":"OTHER","pValue":"0.37","paramType":"Mean Difference (Final Values)","paramValue":"-0.12","statisticalMethod":"Wilcoxon (Mann-Whitney)"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.25","value":"0.00"},{"groupId":"OG001","spread":"0.28","value":"0.06"}]}],"title":"Fingertips"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.26","value":"0.08"},{"groupId":"OG001","spread":"0.27","value":"0.13"}]}],"title":"Thenar Eminence"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.36","value":"0.09"},{"groupId":"OG001","spread":"0.44","value":"-0.03"}]}],"title":"Volar Forearm"}],"denoms":[{"counts":[{"groupId":"OG000","value":"17"},{"groupId":"OG001","value":"19"}],"units":"Participants"}],"description":"Touch detection thresholds are determined using the up/down method with calibrated von Frey monofilaments,\n\nStarting with a 0.5mN force, the von Frey monofilament is applied for approximately 1 sec. If the subject fails to detect the stimulus, then the next higher force von Frey monofilament is applied. When the subject detects the presence of the stimulus, the next lower von Frey is administered. The up/down test sequence continues until the same force filament is detected for three additional applications. The force of that filament is then assigned as the touch threshold","dispersionType":"Standard Deviation","groups":[{"description":"Participants received one pill by mouth on Day 1. Staring on Day 2, 2 times a day (every 12 hours) by mouth for 10 weeks.","id":"OG000","title":"Placebo Group"},{"description":"Participants received minocycline 200 mg orally for 1 dose, then 100 mg orally every 12 hours for 10 weeks beginning at initiation of induction therapy for multiple myeloma","id":"OG001","title":"Minocycline Group"}],"paramType":"MEAN","reportingStatus":"POSTED","timeFrame":"baseline and week 10","title":"The Difference Between Touch Detection Thresholds From the Sensorimotor Evaluation at Baseline and After 10 Weeks of Induction Therapy.","type":"PRIMARY","unitOfMeasure":"mN"}