{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"45.0"},{"groupId":"OG001","value":"75.0"},{"groupId":"OG002","value":"52.6"},{"groupId":"OG003","value":"45.0"},{"groupId":"OG004","value":"61.5"},{"groupId":"OG005","value":"58.3"},{"groupId":"OG006","value":"70.0"}]}],"title":"Headache Absent"},{"categories":[{"measurements":[{"groupId":"OG000","value":"30.0"},{"groupId":"OG001","value":"10.0"},{"groupId":"OG002","value":"36.8"},{"groupId":"OG003","value":"45.0"},{"groupId":"OG004","value":"7.7"},{"groupId":"OG005","value":"8.3"},{"groupId":"OG006","value":"0.0"}]}],"title":"Headache Mild"},{"categories":[{"measurements":[{"groupId":"OG000","value":"25.0"},{"groupId":"OG001","value":"15.0"},{"groupId":"OG002","value":"10.5"},{"groupId":"OG003","value":"10.0"},{"groupId":"OG004","value":"30.8"},{"groupId":"OG005","value":"33.3"},{"groupId":"OG006","value":"20.0"}]}],"title":"Headache Moderate"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"0"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"0"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"10.0"}]}],"title":"Headache Severe"},{"categories":[{"measurements":[{"groupId":"OG000","value":"80.0"},{"groupId":"OG001","value":"80.0"},{"groupId":"OG002","value":"84.2"},{"groupId":"OG003","value":"85.0"},{"groupId":"OG004","value":"76.9"},{"groupId":"OG005","value":"83.3"},{"groupId":"OG006","value":"80.0"}]}],"title":"Visual Disturbances Absent"},{"categories":[{"measurements":[{"groupId":"OG000","value":"10.0"},{"groupId":"OG001","value":"10.0"},{"groupId":"OG002","value":"10.5"},{"groupId":"OG003","value":"10.0"},{"groupId":"OG004","value":"7.7"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"0"}]}],"title":"Visual Disturbances Mild"},{"categories":[{"measurements":[{"groupId":"OG000","value":"5.0"},{"groupId":"OG001","value":"5.0"},{"groupId":"OG002","value":"5.3"},{"groupId":"OG003","value":"5.0"},{"groupId":"OG004","value":"15.4"},{"groupId":"OG005","value":"16.7"},{"groupId":"OG006","value":"20.0"}]}],"title":"Visual Disturbances Moderate"},{"categories":[{"measurements":[{"groupId":"OG000","value":"5.0"},{"groupId":"OG001","value":"5.0"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"0"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"0"}]}],"title":"Visual Disturbances Severe"},{"categories":[{"measurements":[{"groupId":"OG000","value":"80.0"},{"groupId":"OG001","value":"80.0"},{"groupId":"OG002","value":"73.7"},{"groupId":"OG003","value":"75.0"},{"groupId":"OG004","value":"69.2"},{"groupId":"OG005","value":"58.3"},{"groupId":"OG006","value":"70.0"}]}],"title":"Fatigue Absent"},{"categories":[{"measurements":[{"groupId":"OG000","value":"15.0"},{"groupId":"OG001","value":"15.0"},{"groupId":"OG002","value":"21.1"},{"groupId":"OG003","value":"20.0"},{"groupId":"OG004","value":"30.8"},{"groupId":"OG005","value":"33.3"},{"groupId":"OG006","value":"30.0"}]}],"title":"Fatigue Mild"},{"categories":[{"measurements":[{"groupId":"OG000","value":"5.0"},{"groupId":"OG001","value":"0"},{"groupId":"OG002","value":"5.3"},{"groupId":"OG003","value":"5.0"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"8.3"},{"groupId":"OG006","value":"0"}]}],"title":"Fatigue Moderate"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"5.0"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"0"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"0"}]}],"title":"Fatigue Severe"},{"categories":[{"measurements":[{"groupId":"OG000","value":"55.0"},{"groupId":"OG001","value":"65.0"},{"groupId":"OG002","value":"68.4"},{"groupId":"OG003","value":"65.0"},{"groupId":"OG004","value":"61.5"},{"groupId":"OG005","value":"66.7"},{"groupId":"OG006","value":"70.0"}]}],"title":"Decreased libido Absent"},{"categories":[{"measurements":[{"groupId":"OG000","value":"10.0"},{"groupId":"OG001","value":"10.0"},{"groupId":"OG002","value":"10.5"},{"groupId":"OG003","value":"10.0"},{"groupId":"OG004","value":"23.1"},{"groupId":"OG005","value":"25.0"},{"groupId":"OG006","value":"0"}]}],"title":"Decreased libido Mild"},{"categories":[{"measurements":[{"groupId":"OG000","value":"20.0"},{"groupId":"OG001","value":"10.0"},{"groupId":"OG002","value":"5.3"},{"groupId":"OG003","value":"10.0"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"20.0"}]}],"title":"Decreased libido Moderate"},{"categories":[{"measurements":[{"groupId":"OG000","value":"5.0"},{"groupId":"OG001","value":"15.0"},{"groupId":"OG002","value":"15.8"},{"groupId":"OG003","value":"15.0"},{"groupId":"OG004","value":"15.4"},{"groupId":"OG005","value":"8.3"},{"groupId":"OG006","value":"10.0"}]}],"title":"Decreased libido Severe"},{"categories":[{"measurements":[{"groupId":"OG000","value":"10.0"},{"groupId":"OG001","value":"0"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"0"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"0"}]}],"title":"Decreased libido Very severe"},{"categories":[{"measurements":[{"groupId":"OG000","value":"22.2"},{"groupId":"OG001","value":"11.1"},{"groupId":"OG002","value":"11.1"},{"groupId":"OG003","value":"11.1"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"0"}]}],"title":"Erectile dysfunction Yes"},{"categories":[{"measurements":[{"groupId":"OG000","value":"77.8"},{"groupId":"OG001","value":"88.9"},{"groupId":"OG002","value":"88.9"},{"groupId":"OG003","value":"88.9"},{"groupId":"OG004","value":"100.0"},{"groupId":"OG005","value":"100.0"},{"groupId":"OG006","value":"100.0"}]}],"title":"Erectile dysfunction No"},{"categories":[{"measurements":[{"groupId":"OG000","value":"45.5"},{"groupId":"OG001","value":"55.6"},{"groupId":"OG002","value":"62.5"},{"groupId":"OG003","value":"55.6"},{"groupId":"OG004","value":"60.0"},{"groupId":"OG005","value":"50.0"},{"groupId":"OG006","value":"50.0"}]}],"title":"Regular Menses Yes"},{"categories":[{"measurements":[{"groupId":"OG000","value":"54.5"},{"groupId":"OG001","value":"44.4"},{"groupId":"OG002","value":"37.5"},{"groupId":"OG003","value":"44.4"},{"groupId":"OG004","value":"40.0"},{"groupId":"OG005","value":"50.0"},{"groupId":"OG006","value":"50.0"}]}],"title":"Regular Menses No"}],"denoms":[{"counts":[{"groupId":"OG000","value":"20"},{"groupId":"OG001","value":"20"},{"groupId":"OG002","value":"19"},{"groupId":"OG003","value":"20"},{"groupId":"OG004","value":"13"},{"groupId":"OG005","value":"12"},{"groupId":"OG006","value":"11"}],"units":"Participants"}],"description":"The absence and presence of disease-related symptoms were reported by patients and recorded by the medical staff. Patients classified the symptoms according to a 5-point scale (0 = absent, 1 = mild, 2 = moderate, 3 = severe, 4 = very severe","groups":[{"description":"Baseline of Main Phase","id":"OG000","title":"Baseline"},{"description":"Week 4 of Main Phase","id":"OG001","title":"Week 4"},{"description":"Week 12 of Main Phase","id":"OG002","title":"Week 12"},{"description":"Week 24 of Main Phase","id":"OG003","title":"Week 24"},{"description":"Week 48 of Extension Phase","id":"OG004","title":"Week 48"},{"description":"Week 72 of Extension Phase","id":"OG005","title":"Week 72"},{"description":"Week 96 of Extension Phase","id":"OG006","title":"Week 96"}],"paramType":"NUMBER","populationDescription":"number of participants varied across visits","reportingStatus":"POSTED","timeFrame":"Baseline and at weeks 4, 12,24,48,72, 96","title":"Percentage of Participants Reporting Absence and Presence of Relevant Disease-related Symptoms (FAS)","type":"SECONDARY","unitOfMeasure":"percentage of participants"}