{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"-52.11","upperLimit":"125.94","value":"36.92"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"20"}],"units":"Participants"}],"title":"Main Week 4"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"-42.19","upperLimit":"120.91","value":"39.36"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"19"}],"units":"Participants"}],"title":"Main Week 12"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"-32.79","upperLimit":"48.74","value":"7.98"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"20"}],"units":"Participants"}],"title":"Main Week 24"}],"denoms":[{"counts":[{"groupId":"OG000","value":"20"}],"units":"Participants"}],"description":"Tumor volume was evaluated by MRI. MRIs were performed and processed according to the guidelines of the central evaluator's facility. The pituitary adenomas were measured by a neuro-radiologist, using manual tracing together with the imaging analysis software. The largest diameter at any plan determined the maximum diameter of the tumor.","dispersionType":"95% Confidence Interval","groups":[{"description":"All patients will receive pasireotide LAR (long acting release) 60 mg every 28 ± 3 days for 24 weeks","id":"OG000","title":"Pasireotide LAR"}],"paramType":"MEAN","populationDescription":"number of participants with evaluable data varied across visits","reportingStatus":"POSTED","timeFrame":"baseline to week 4, 12, 24","title":"Tumor Volume Percent Change From Baseline in Main Phase (FAS)","type":"SECONDARY","unitOfMeasure":"percent change"}