{"anticipatedPostingDate":"2026-12","denomUnitsSelected":"Participants","description":"Time from date of randomization (2nd Registration) to date of invasive local or regional recurrence. Participants last known to be alive without recurrence are censored at their last contact date. Participants with distant recurrence, second primary cancer or death are censored at the time of that event.\n\nInvasive recurrence is defined as: appearance of any new invasive lesion(s) during or after protocol treatment. Whenever possible, recurrences should be documented histologically. Invasive recurrence includes local, regional, or distant recurrence with an invasive component. A new diagnosis of ipsilateral or contralateral DCIS without an invasive component is not considered to be a recurrence.","reportingStatus":"NOT_POSTED","timeFrame":"From date of randomization to a maximum of 5.5 years or death","title":"Local Disease-Free Interval (LDFI)","type":"SECONDARY"}