{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"8.78","value":"77.7"},{"groupId":"OG001","spread":"9.73","value":"77.1"}]}],"title":"Diastolic BP, Baseline, n=89,83"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"10.12","value":"74.0"},{"groupId":"OG001","spread":"10.88","value":"74.6"}]}],"title":"Diastolic BP, Week 4, n=81, 78"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"9.14","value":"74.6"},{"groupId":"OG001","spread":"9.54","value":"72.7"}]}],"title":"Diastolic BP, Week 8, n=70, 73"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"7.70","value":"75.2"},{"groupId":"OG001","spread":"11.64","value":"74.3"}]}],"title":"Diastolic BP, Week 12, n=68, 62"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"10.01","value":"73.2"},{"groupId":"OG001","spread":"9.40","value":"71.4"}]}],"title":"Diastolic BP, Week 16, n=52, 52"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"9.98","value":"73.6"},{"groupId":"OG001","spread":"9.67","value":"71.7"}]}],"title":"Diastolic BP, Week 20, n=29, 34"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"7.87","value":"74.7"},{"groupId":"OG001","spread":"9.99","value":"72.7"}]}],"title":"Diastolic BP, Week 24, n=22, 25"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"6.98","value":"73.9"},{"groupId":"OG001","spread":"8.37","value":"76.5"}]}],"title":"Diastolic BP, Week 28, n=15, 17"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"9.47","value":"73.1"},{"groupId":"OG001","spread":"9.64","value":"73.6"}]}],"title":"Diastolic BP, Week 32, n=9, 7"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"7.78","value":"75.5"},{"comment":"Standard deviation could not be calculated because only one participant was analyzed in this treatment group at this time point.","groupId":"OG001","spread":"NA","value":"93.0"}]}],"title":"Diastolic BP, Week 36, n=2, 1"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"16.73","value":"126.6"},{"groupId":"OG001","spread":"14.17","value":"123.9"}]}],"title":"Systolic BP, Baseline, n=89, 83"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"13.68","value":"122.2"},{"groupId":"OG001","spread":"15.37","value":"121.9"}]}],"title":"Systolic BP, Week 4, n=81, 78"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"12.71","value":"123.0"},{"groupId":"OG001","spread":"14.53","value":"117.3"}]}],"title":"Systolic BP, Week 8, n=70, 73"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"14.74","value":"123.6"},{"groupId":"OG001","spread":"14.21","value":"120.1"}]}],"title":"Systolic BP, Week 12, 68, 62"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"17.70","value":"124.7"},{"groupId":"OG001","spread":"11.67","value":"119.9"}]}],"title":"Systolic BP, Week 16, n=52, 52"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"16.02","value":"123.7"},{"groupId":"OG001","spread":"13.51","value":"118.9"}]}],"title":"Systolic BP, Week 20, n=29, 34"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"17.80","value":"126.3"},{"groupId":"OG001","spread":"16.63","value":"120.9"}]}],"title":"Systolic BP, Week 24, n=22, 25"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"17.03","value":"122.2"},{"groupId":"OG001","spread":"14.32","value":"120.8"}]}],"title":"Systolic BP, Week 28, n=15, 17"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"14.84","value":"122.8"},{"groupId":"OG001","spread":"10.01","value":"117.7"}]}],"title":"Systolic BP, Week 32, n=9, 7"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"13.44","value":"119.5"},{"comment":"Standard deviation could not be calculated because only one participant was analyzed in this treatment group at this time point.","groupId":"OG001","spread":"NA","value":"128.0"}]}],"title":"Systolic BP, Week 36, n=2, 1"}],"denoms":[{"counts":[{"groupId":"OG000","value":"89"},{"groupId":"OG001","value":"83"}],"units":"Participants"}],"description":"Systolic and diastolic blood pressure were measured for all treated participants.","dispersionType":"Standard Deviation","groups":[{"description":"Participants who received no prior local therapy for brain metastasis received GSK2118436 150 mg capsules either one hour before or 2 hours after a meal twice daily until evidence of disease progression, death, or unacceptable adverse events.","id":"OG000","title":"GSK2118436 150 mg: No Prior Local Therapy"},{"description":"Participants who received prior local therapy for brain metastasis received GSK2118436 150 mg capsules either one hour before or 2 hours after a meal twice daily until evidence of disease progression, death, or unacceptable adverse events.","id":"OG001","title":"GSK2118436 150 mg: Prior Local Therapy"}],"paramType":"MEAN","populationDescription":"ATS Population. Only those participants with data available at the indicated time points were analyzed.","reportingStatus":"POSTED","timeFrame":"Baseline; Weeks 4, 8, 12, 16, 20, 24, 28, 32, and 36","title":"Mean Blood Pressure at Baseline and Weeks 4, 8, 12, 16, 20, 24, 28, 32, and 36","type":"SECONDARY","unitOfMeasure":"millimeters of mercury (mmHg)"}