{"denoms":[{"counts":[{"groupId":"BG000","value":"214"},{"groupId":"BG001","value":"108"},{"groupId":"BG002","value":"322"}],"units":"Participants"}],"groups":[{"description":"Participants with histologically confirmed cutaneous advanced or metastatic melanoma (Stage IIIC or Stage IV), with a BRAF (a human gene encoding for protein called B-Raf, which is involved in a signaling pathway and is important for cell growth) V600 E/K mutation-positive tumor sample as determined via the central BRAF mutation assay, received a Trametinib 2 milligram (mg) tablet once daily until disease progression, death, or withdrawal.","id":"BG000","title":"Trametinib"},{"description":"Participants with histologically confirmed cutaneous advanced or metastatic melanoma (Stage IIIC or Stage IV), with a BRAF V600 E/K mutation-positive tumor sample as determined via the central BRAF mutation assay, received an intravenous (IV) dose of Dacarbazine 1000 mg per square meter every 3 weeks or Paclitaxel 175 mg per square meter every 3 weeks at the discretion of the investigator, provided the participant had not received that type of chemotherapy before randomization, until disease progression, death, or withdrawal.","id":"BG001","title":"Chemotherapy"},{"description":"Total of all reporting groups","id":"BG002","title":"Total"}],"measures":[{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","spread":"12.97","value":"54.3"},{"groupId":"BG001","spread":"13.56","value":"52.8"},{"groupId":"BG002","spread":"13.17","value":"53.8"}]}]}],"dispersionType":"STANDARD_DEVIATION","paramType":"MEAN","title":"Age, Continuous","unitOfMeasure":"Years"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"94"},{"groupId":"BG001","value":"55"},{"groupId":"BG002","value":"149"}],"title":"Female"},{"measurements":[{"groupId":"BG000","value":"120"},{"groupId":"BG001","value":"53"},{"groupId":"BG002","value":"173"}],"title":"Male"}]}],"paramType":"COUNT_OF_PARTICIPANTS","title":"Sex: Female, Male","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"2"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"2"}],"title":"White - Arabic/North African Heritage"},{"measurements":[{"groupId":"BG000","value":"212"},{"groupId":"BG001","value":"107"},{"groupId":"BG002","value":"319"}],"title":"White - White/Caucasian/European Heritage"},{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"1"},{"groupId":"BG002","value":"1"}],"title":"White - Mixed Race"}],"title":"Race/Ethnicity, Customized"}],"paramType":"COUNT_OF_PARTICIPANTS","title":"Race/Ethnicity, Customized","unitOfMeasure":"Participants"}]}