{"analyses":[{"groupIds":["OG000","OG001","OG002"],"nonInferiorityComment":"Other, trend test.","nonInferiorityType":"OTHER","pValue":"0.008","statisticalMethod":"Jonckheere-Terpstra test for trend"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"15","upperLimit":"19.7","value":"15"},{"groupId":"OG001","lowerLimit":"7.6","upperLimit":"32.5","value":"19.4"},{"groupId":"OG002","lowerLimit":"10.5","upperLimit":"37.6","value":"20.9"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"10"},{"groupId":"OG001","value":"10"},{"groupId":"OG002","value":"7"}],"units":"Participants"}],"description":"Microvessel density was estimated by determining the average number of cluster of differentiation 34 (CD34)-stained microvessels in 10 areas of maximal MVD counted at a high-power field (h.p.f. x 500 magnification). Large vessels and vessels in the periosteum on bone were excluded. Areas of staining with no discrete breaks were counted as a single vessel. The presence of a lumen was not required.","dispersionType":"Full Range","groups":[{"description":"MGUS (Monoclonal gammopathy of undetermined significance) is a premalignant plasma cell proliferative disorder.","id":"OG000","title":"MGUS (Monoclonal Gammopathy of Undetermined Significance)"},{"description":"Smoldering multiple myeloma (SMM)is a premalignant plasma cell proliferative disorder.","id":"OG001","title":"SMM (Smoldering Multiple Myeloma)"},{"description":"Multiple myeloma is a plasma cell neoplasm.","id":"OG002","title":"MM (Multiple Myeloma)"}],"paramType":"MEDIAN","populationDescription":"Three patients with MM did not undergo bone marrow biopsies and were not included in this analysis.","reportingStatus":"POSTED","timeFrame":"60 days","title":"Comparison of Microvessel Density (MVD) Among Patients With MGUS, SMM, and MM","type":"SECONDARY","unitOfMeasure":"microvessels/hpf"}