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Cycle 13 and beyond, single agent ixazomib 1.68, 2.23, 2.97 or 3.95 mg/m\\^2, capsules, orally, once on Days 1, 8 and 15 of a 28-day cycle until disease progression or unacceptable toxicity.","id":"EG000","otherNumAffected":15,"otherNumAtRisk":15,"seriousNumAffected":8,"seriousNumAtRisk":15,"title":"Phase 1: Ixazomib + Lenalidomide + Dexamethasone"},{"description":"In phase 2, ixazomib 4.0 mg fixed dose, capsules, orally, once, on Days 1, 8 and 15; plus dexamethasone 40 mg, tablets, orally, once on Days 1, 8, 15 and 22; and lenalidomide 25 mg, capsules, orally, once on Days 1 through 21 of a 28-day cycle for up to 12 cycles. Cycle 13 and beyond, single agent ixazomib 4.0 mg fixed dose, capsules, orally, once on Days 1, 8 and 15 of a 28-day cycle until disease progression or unacceptable toxicity.","id":"EG001","otherNumAffected":50,"otherNumAtRisk":50,"seriousNumAffected":20,"seriousNumAtRisk":50,"title":"Phase 2: Ixazomib 4.0 mg + Lenalidomide + Dexamethasone"}],"frequencyThreshold":"5","otherEvents":[{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"MedDRA (16.0)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":15},{"groupId":"EG001","numAffected":7,"numAtRisk":50}],"term":"Leukopenia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"MedDRA (16.0)","stats":[{"groupId":"EG000","numAffected":3,"numAtRisk":15},{"groupId":"EG001","numAffected":7,"numAtRisk":50}],"term":"Lymphopenia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system 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