{"analyses":[{"ciNumSides":"TWO_SIDED","groupDescription":"Comparison between arms at Day 28 of treatment for the Digit Span Test score-Forward test","groupIds":["OG000","OG001"],"nonInferiorityType":"SUPERIORITY_OR_OTHER","pValue":"0.636","statisticalMethod":"Wilcoxon (Mann-Whitney)","testedNonInferiority":false},{"ciNumSides":"TWO_SIDED","groupDescription":"Comparison between arms at Day 28 of treatment for the Digit Span Test score-Backward test","groupIds":["OG000","OG001"],"nonInferiorityType":"SUPERIORITY_OR_OTHER","pValue":"0.531","statisticalMethod":"Wilcoxon (Mann-Whitney)","testedNonInferiority":false},{"ciNumSides":"TWO_SIDED","groupDescription":"Day 1 vs. Day 28 of treatment for the Placebo-First arm-Digit Span Test score Forward test","groupIds":["OG001"],"nonInferiorityType":"SUPERIORITY_OR_OTHER","pValue":"0.037","statisticalMethod":"Wilcoxon (Mann-Whitney)","testedNonInferiority":false},{"ciNumSides":"TWO_SIDED","groupDescription":"Day 1 vs. Day 28 of treatment for the Placebo-First arm-Digit Span Test score Backward test","groupIds":["OG001"],"nonInferiorityType":"SUPERIORITY_OR_OTHER","pValue":"0.656","statisticalMethod":"t-test, 2 sided","testedNonInferiority":false},{"ciNumSides":"TWO_SIDED","groupDescription":"Day 1 vs. day 28 of treatment for the Armodafinil arm-Digit Span Test score-Forward test","groupIds":["OG000"],"nonInferiorityType":"SUPERIORITY_OR_OTHER","pValue":"0.028","statisticalMethod":"t-test, 2 sided","testedNonInferiority":false},{"ciNumSides":"TWO_SIDED","groupDescription":"Day 1 vs. day 28 of treatment for the Armodafinil arm-Digit Span Test score-Backward test","groupIds":["OG000"],"nonInferiorityType":"SUPERIORITY_OR_OTHER","pValue":"0.805","statisticalMethod":"t-test, 2 sided","testedNonInferiority":false},{"ciNumSides":"TWO_SIDED","groupDescription":"Day 28 vs. day 56 of treatment for the Armodafinil arm-Digit Span Test score-Forward test","groupIds":["OG000"],"nonInferiorityType":"SUPERIORITY_OR_OTHER","pValue":"0.692","statisticalMethod":"t-test, 2 sided","testedNonInferiority":false},{"ciNumSides":"TWO_SIDED","groupDescription":"Day 28 vs. day 56 of treatment for the Armodafinil arm-Digit Span Test score-Backward test","groupIds":["OG000"],"nonInferiorityType":"SUPERIORITY_OR_OTHER","pValue":"0.863","statisticalMethod":"t-test, 2 sided","testedNonInferiority":false}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"2.7","value":"9.5"},{"groupId":"OG001","spread":"2.6","value":"9.8"}]}],"title":"Forward-Day 1 (n=18, 23)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"2.0","value":"7.3"},{"groupId":"OG001","spread":"2.4","value":"6.3"}]}],"title":"Backward-Day 1 (n=18, 23)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"3.0","value":"10.6"},{"groupId":"OG001","spread":"2.3","value":"10.4"}]}],"title":"Forward-Day 28 (n=19, 23)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"2.6","value":"7.0"},{"groupId":"OG001","spread":"2.6","value":"7.0"}]}],"title":"Backward- Day 28 (n=19, 23)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"2.8","value":"10.3"},{"comment":"Day 56 data was only evaluated for the Armodafinil arm","groupId":"OG001","spread":"NA","value":"NA"}]}],"title":"Forward-Day 56 (n=15)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"2.8","value":"7.4"},{"comment":"Day 56 data was only evaluated for the Armodafinil arm","groupId":"OG001","spread":"NA","value":"NA"}]}],"title":"Backward-Day 56 (n=15)"}],"denoms":[{"counts":[{"groupId":"OG000","value":"25"},{"groupId":"OG001","value":"25"}],"units":"Participants"}],"description":"Test evaluates working memory and attention. The test consists of repeat numeric sequences of 2 to 9 numbers forward or backwards and evaluates the number of items from a sequence correctly named. Higher scores = better performance.","dispersionType":"Standard Deviation","groups":[{"description":"The patients receive armodafinil for all 56 days of the study.\n\nArmodafinil taken orally at 150 mg daily.","id":"OG000","title":"Armodafinil"},{"description":"These patients receive a placebo for the first 28 days of the study. They are then crossed over and receive armodafinil for the final 28 days of the study (days 29-56).\n\nPlacebo taken orally at 150 mg daily. Armodafinil taken orally at 150 mg daily.","id":"OG001","title":"Placebo-First"}],"paramType":"MEAN","reportingStatus":"POSTED","timeFrame":"Day 1, Day 28 and Day 56","title":"Digit Span Test Score","type":"PRIMARY","unitOfMeasure":"Number of correct items"}