{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.23","upperLimit":"2.19","value":"1.65"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"15"}],"units":"Participants"}],"description":"Geometric mean ratio (Fed/Fasted) for PCI-32765 AUClast. The data were collected at 0, 0.5, 1, 2, 4, 6, 24 h post-dose. The AUClast was calculated from 0 up to 24 hours post-dose.","dispersionType":"90% Confidence Interval","groups":[{"description":"PCI-32765: 420 mg daily","id":"OG000","title":"Food Effect Cohort"}],"paramType":"NUMBER","populationDescription":"Note: 16 subjects were participated in food effect cohort. However, the PK parameters for 1 subject under Fasted treatment period cannot be reliably estimated. The data for this subject were excluded from Fed/Fasted comparison.","reportingStatus":"POSTED","timeFrame":"Fed was assessed on either Day 8 or Day 15 and Fasted was assessed on the remaining day as cross-over design.","title":"Food Effect Cohort Assessments","type":"SECONDARY"}