{"eventGroups":[{"description":"Standard of care for prevention and management of oral mucositis (0.9% Sodium Chloride irrigation solution): Patients randomized to this group will be instructed to rinse their mouths twice, with 1 ounce (30 ml) of room temperature 0.9% NaCl (normal saline), 4 times daily after admission and until end of study.\n\n0.9% Sodium Chloride irrigation solution: Patients randomized to this group will be instructed to rinse their mouths twice, with 1 ounce (30 ml) of room temperature 0.9% NaCl (normal saline), 4 times daily after admission and until end of study","id":"EG000","otherNumAffected":0,"otherNumAtRisk":38,"seriousNumAffected":0,"seriousNumAtRisk":38,"title":"0.9% Sodium Chloride Irrigation Solution"},{"description":"Cryotherapy (ice chips): Patients randomized to this group, on day -2 and -1, will be instructed to place approximately 1 ounce of crushed ice in their mouths 15 minutes prior to the initiation of melphalan infusion. The ice will be allowed to melt and should be replenish as soon as it had completely melted. Patients will be instructed to continue this procedure during the melphalan infusion and for 90 minutes after the end of the infusion. After patients are done with the cryotherapy they will follow the standard of care for prevention and management of oral mucositis until the end of the study.","id":"EG001","otherNumAffected":0,"otherNumAtRisk":40,"seriousNumAffected":0,"seriousNumAtRisk":40,"title":"Cryotherapy (Ice Chips)"},{"description":"Patients randomized to this group will be instructed to rinse their mouths with Caphosol 4 times daily after admission and until end of study.\n\nCalcium phosphate (Caphosol) Ca2+/PO43- mouth rinse: Patients randomized to this group will be instructed to rinse their mouths with Caphosol 4 times daily after admission and until end of study.","id":"EG002","otherNumAffected":0,"otherNumAtRisk":39,"seriousNumAffected":0,"seriousNumAtRisk":39,"title":"Calcium Phosphate (Caphosol) Mouth Rinse"}],"frequencyThreshold":"5"}