{"description":"Safety population included patients who received at least 1 dose of study drug. Adverse Events are reported for Stage 1a (GClb and Clb arms). In Stage 1a, 4 patients randomized to the RClb arm actually received obinutuzumab and were included in the GClb arm for analysis.","eventGroups":[{"description":"Participants received 1000 mg obinutuzumab intravenous (IV) infusion, on Days 1 \\[first infusion split 100 mg on Day 1 and 900 mg on Day 2 as per protocol amendment\\], 8 and 15 in Cycle 1 and Day 1 in Cycles 2-6 (28-day cycles) plus chlorambucil 0.5 mg/kg orally on Day 1 and 15 of each 28-day cycle (6 Cycles).","id":"EG000","otherNumAffected":215,"otherNumAtRisk":241,"seriousNumAffected":113,"seriousNumAtRisk":241,"title":"Obinutuzumab + Chlorambucil (GClb)"},{"description":"Participants received chlorambucil 0.5 mg/kg orally on Day 1 and 15 of each 28-day cycle (6 Cycles). Participants with Progressive Disease or within 6 months of follow-up were allowed to cross over to receive obinutuzumab + chlorambucil.","id":"EG001","otherNumAffected":89,"otherNumAtRisk":116,"seriousNumAffected":45,"seriousNumAtRisk":116,"title":"Chlorambucil (Clb)"},{"description":"Subjects in Clb arm who progressed during/within 6 months after end of Clb treatment had opportunity to cross over to GClb arm at discretion of investigator. Subjects received 1000 mg obinutuzumab IV infusion, on Day 1 \\[First infusion split 100 mg on Day 1 and 900 mg on Day 2 as per protocol amendment\\], 8 and 15 in Cycle 1 and Day 1 of Cycles 2-6 (28-day cycles) plus chlorambucil 0.5 milligram per kilogram of body weight (mg/kg) orally on Day 1 and 15 of each 28-day cycle (6 Cycles).","id":"EG002","otherNumAffected":23,"otherNumAtRisk":30,"seriousNumAffected":8,"seriousNumAtRisk":30,"title":"Crossover Subjects: Obinutuzumab + Chlorambucil (GClb)"}],"frequencyThreshold":"5","otherEvents":[{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"MedDRA 15.0","stats":[{"groupId":"EG000","numAffected":99,"numAtRisk":241},{"groupId":"EG001","numAffected":21,"numAtRisk":116},{"groupId":"EG002","numAffected":12,"numAtRisk":30}],"term":"Neutropenia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"MedDRA 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15.0","stats":[{"groupId":"EG000","numAffected":13,"numAtRisk":241},{"groupId":"EG001","numAffected":14,"numAtRisk":116},{"groupId":"EG002","numAffected":0,"numAtRisk":30}],"term":"Vomiting"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Injury, poisoning and procedural complications","sourceVocabulary":"MedDRA 15.0","stats":[{"groupId":"EG000","numAffected":147,"numAtRisk":241},{"groupId":"EG001","numAffected":0,"numAtRisk":116},{"groupId":"EG002","numAffected":15,"numAtRisk":30}],"term":"Infusion related reaction"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"General disorders","sourceVocabulary":"MedDRA 15.0","stats":[{"groupId":"EG000","numAffected":25,"numAtRisk":241},{"groupId":"EG001","numAffected":8,"numAtRisk":116},{"groupId":"EG002","numAffected":2,"numAtRisk":30}],"term":"Pyrexia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"General disorders","sourceVocabulary":"MedDRA 15.0","stats":[{"groupId":"EG000","numAffected":16,"numAtRisk":241},{"groupId":"EG001","numAffected":12,"numAtRisk":116},{"groupId":"EG002","numAffected":1,"numAtRisk":30}],"term":"Fatigue"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"General disorders","sourceVocabulary":"MedDRA 15.0","stats":[{"groupId":"EG000","numAffected":17,"numAtRisk":241},{"groupId":"EG001","numAffected":8,"numAtRisk":116},{"groupId":"EG002","numAffected":1,"numAtRisk":30}],"term":"Asthenia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Respiratory, thoracic and mediastinal disorders","sourceVocabulary":"MedDRA 15.0","stats":[{"groupId":"EG000","numAffected":22,"numAtRisk":241},{"groupId":"EG001","numAffected":8,"numAtRisk":116},{"groupId":"EG002","numAffected":4,"numAtRisk":30}],"term":"Cough"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Respiratory, thoracic and mediastinal disorders","sourceVocabulary":"MedDRA 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