{"analyses":[{"ciLowerLimit":"-4.9331","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"1.5841","estimateComment":"A positive difference between the treatment groups favors the panitumumab group.","groupDescription":"Repeated measures mixed model includes treatment, geographic region, ECOG score, assessment week, and treatment by assessment week interaction as fixed effects, and subjects a random effect. An unstructured covariance matrix is used in the mixed model.","groupIds":["OG000","OG001"],"nonInferiorityType":"SUPERIORITY_OR_OTHER_LEGACY","paramType":"LS Mean Difference","paramValue":"-1.6745"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0.8842","upperLimit":"7.0722","value":"3.9782"},{"groupId":"OG001","lowerLimit":"-0.8532","upperLimit":"5.4605","value":"2.3037"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"149"},{"groupId":"OG001","value":"142"}],"units":"Participants"}],"description":"The EQ-5D is a standardized instrument for use as a generic measure of health outcome. The VAS asks respondents to rate their present health status on a 0 - 100 scale, with 0 labeled as \"Worst imaginable health state\" and 100 labeled as \"Best imaginable health state.\" The VAS score is determined by observing the point at which the participant's hand drawn line intersects the scale.","dispersionType":"95% Confidence Interval","groups":[{"description":"Cetuximab 400 mg/m\\^2 as an initial dose, followed by 250 mg/m\\^2 intravenously (IV) every 7 days.","id":"OG000","title":"Cetuximab"},{"description":"Panitumumab 6 mg/kg IV every 14 days.","id":"OG001","title":"Panitumumab"}],"paramType":"LEAST_SQUARES_MEAN","populationDescription":"Patient reported outcomes (PRO) analysis set participants with available data","reportingStatus":"POSTED","timeFrame":"From Study Day 1 through the last day of treatment or disease progression, up to Week 85.","title":"Change From Baseline in EuroQOL 5 Dimension (EQ-5D) Visual Analog Scale (VAS)","type":"SECONDARY","unitOfMeasure":"scores on a scale"}