{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0.6","upperLimit":"9.8","value":"5.21"},{"groupId":"OG001","lowerLimit":"1.3","upperLimit":"8.8","value":"4.46"}]}],"title":"Baseline estradiol"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1","upperLimit":"8.7","value":"5.23"},{"groupId":"OG001","lowerLimit":"1.9","upperLimit":"18","value":"6.72"}]}],"title":"Week 12 estradiol"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"36.4","upperLimit":"121.2","value":"70.92"},{"groupId":"OG001","lowerLimit":"19.9","upperLimit":"114.5","value":"68.29"}]}],"title":"Baseline follicle stimulating hormone (FSH)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"33.6","upperLimit":"115.9","value":"71.67"},{"groupId":"OG001","lowerLimit":"23.4","upperLimit":"90.5","value":"63.28"}]}],"title":"Week 12 follicle stimulating hormone (FSH)"}],"denoms":[{"counts":[{"groupId":"OG000","value":"12"},{"groupId":"OG001","value":"19"}],"units":"Participants"}],"description":"To determine the change in estradiol and follicle stimulating hormone (FSH) from baseline to twelve weeks in postmenopausal women receiving adjuvant aromatase inhibitors during treatment with low dose vaginal 10 µg 17- β estradiol.","dispersionType":"Full Range","groups":[{"description":"This is a prospective longitudinal pilot study, and the targeted patient population is postmenopausal women with breast cancer being treated with adjuvant aromatase inhibitors who are initiated on vaginal 17β-estradiol to relieve symptoms of atrophic vaginitis.","id":"OG000","title":"Letrozole"},{"description":"This is a prospective longitudinal pilot study, and the targeted patient population is postmenopausal women with breast cancer being treated with adjuvant aromatase inhibitors who are initiated on vaginal 17β-estradiol to relieve symptoms of atrophic vaginitis.","id":"OG001","title":"Anastrozole"}],"paramType":"MEAN","reportingStatus":"POSTED","timeFrame":"12 weeks","title":"Change in Serum Estradiol From Baseline to Week 12","type":"PRIMARY","unitOfMeasure":"pg/ml"}