{"denoms":[{"counts":[{"groupId":"BG000","value":"315"},{"groupId":"BG001","value":"318"},{"groupId":"BG002","value":"633"}],"units":"Participants"}],"groups":[{"description":"Necitumumab: 800 mg (absolute dose) on Days 1 and 8 of every 3-week cycle, administered as an I.V. infusion\n\nPemetrexed: 500 mg/m2 I.V. on Day 1 of every 3-week cycle, for a maximum of six cycles\n\nCisplatin: 75 mg/m2 I.V. on Day 1 of every 3-week cycle, for a maximum of six cycles","id":"BG000","title":"Necitumumab + Pemetrexed + Cisplatin"},{"description":"Pemetrexed + Cisplatin\n\nPemetrexed: 500 mg/m2 I.V. on Day 1 of every 3-week cycle, for a maximum of six cycles\n\nCisplatin: 75 mg/m2 I.V. on Day 1 of every 3-week cycle, for a maximum of six cycles","id":"BG001","title":"Pemetrexed + Cisplatin"},{"description":"Total of all reporting groups","id":"BG002","title":"Total"}],"measures":[{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","lowerLimit":"26","upperLimit":"84","value":"61.0"},{"groupId":"BG001","lowerLimit":"34","upperLimit":"88","value":"60.0"},{"groupId":"BG002","lowerLimit":"26","upperLimit":"88","value":"61.00"}]}]}],"dispersionType":"FULL_RANGE","paramType":"MEDIAN","title":"Age, Customized","unitOfMeasure":"years"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"101"},{"groupId":"BG001","value":"108"},{"groupId":"BG002","value":"209"}],"title":"Female"},{"measurements":[{"groupId":"BG000","value":"214"},{"groupId":"BG001","value":"210"},{"groupId":"BG002","value":"424"}],"title":"Male"}]}],"paramType":"COUNT_OF_PARTICIPANTS","title":"Sex: Female, Male","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"47"},{"groupId":"BG001","value":"46"},{"groupId":"BG002","value":"93"}],"title":"Hispanic or Latino"},{"measurements":[{"groupId":"BG000","value":"268"},{"groupId":"BG001","value":"272"},{"groupId":"BG002","value":"540"}],"title":"Not Hispanic or Latino"},{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"0"}],"title":"Unknown or Not Reported"}]}],"paramType":"COUNT_OF_PARTICIPANTS","title":"Ethnicity (NIH/OMB)","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"0"}],"title":"American Indian or Alaska Native"},{"measurements":[{"groupId":"BG000","value":"2"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"2"}],"title":"Asian"},{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"0"}],"title":"Native Hawaiian or Other Pacific Islander"},{"measurements":[{"groupId":"BG000","value":"8"},{"groupId":"BG001","value":"9"},{"groupId":"BG002","value":"17"}],"title":"Black or African American"},{"measurements":[{"groupId":"BG000","value":"292"},{"groupId":"BG001","value":"298"},{"groupId":"BG002","value":"590"}],"title":"White"},{"measurements":[{"groupId":"BG000","value":"13"},{"groupId":"BG001","value":"11"},{"groupId":"BG002","value":"24"}],"title":"More than one race"},{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"0"}],"title":"Unknown or Not Reported"}]}],"paramType":"COUNT_OF_PARTICIPANTS","title":"Race (NIH/OMB)","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"16"},{"groupId":"BG001","value":"13"},{"groupId":"BG002","value":"29"}]}],"title":"Russian Federation"},{"categories":[{"measurements":[{"groupId":"BG000","value":"21"},{"groupId":"BG001","value":"31"},{"groupId":"BG002","value":"52"}]}],"title":"Romania"},{"categories":[{"measurements":[{"groupId":"BG000","value":"23"},{"groupId":"BG001","value":"22"},{"groupId":"BG002","value":"45"}]}],"title":"Hungary"},{"categories":[{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"1"},{"groupId":"BG002","value":"1"}]}],"title":"United States"},{"categories":[{"measurements":[{"groupId":"BG000","value":"11"},{"groupId":"BG001","value":"11"},{"groupId":"BG002","value":"22"}]}],"title":"United Kingdom"},{"categories":[{"measurements":[{"groupId":"BG000","value":"6"},{"groupId":"BG001","value":"1"},{"groupId":"BG002","value":"7"}]}],"title":"Portugal"},{"categories":[{"measurements":[{"groupId":"BG000","value":"40"},{"groupId":"BG001","value":"27"},{"groupId":"BG002","value":"67"}]}],"title":"Spain"},{"categories":[{"measurements":[{"groupId":"BG000","value":"5"},{"groupId":"BG001","value":"10"},{"groupId":"BG002","value":"15"}]}],"title":"Greece"},{"categories":[{"measurements":[{"groupId":"BG000","value":"2"},{"groupId":"BG001","value":"1"},{"groupId":"BG002","value":"3"}]}],"title":"Canada"},{"categories":[{"measurements":[{"groupId":"BG000","value":"8"},{"groupId":"BG001","value":"11"},{"groupId":"BG002","value":"19"}]}],"title":"Austria"},{"categories":[{"measurements":[{"groupId":"BG000","value":"8"},{"groupId":"BG001","value":"9"},{"groupId":"BG002","value":"17"}]}],"title":"Belgium"},{"categories":[{"measurements":[{"groupId":"BG000","value":"37"},{"groupId":"BG001","value":"35"},{"groupId":"BG002","value":"72"}]}],"title":"Brazil"},{"categories":[{"measurements":[{"groupId":"BG000","value":"28"},{"groupId":"BG001","value":"24"},{"groupId":"BG002","value":"52"}]}],"title":"Poland"},{"categories":[{"measurements":[{"groupId":"BG000","value":"17"},{"groupId":"BG001","value":"19"},{"groupId":"BG002","value":"36"}]}],"title":"Italy"},{"categories":[{"measurements":[{"groupId":"BG000","value":"2"},{"groupId":"BG001","value":"5"},{"groupId":"BG002","value":"7"}]}],"title":"South Africa"},{"categories":[{"measurements":[{"groupId":"BG000","value":"3"},{"groupId":"BG001","value":"1"},{"groupId":"BG002","value":"4"}]}],"title":"Slovakia"},{"categories":[{"measurements":[{"groupId":"BG000","value":"6"},{"groupId":"BG001","value":"8"},{"groupId":"BG002","value":"14"}]}],"title":"Australia"},{"categories":[{"measurements":[{"groupId":"BG000","value":"7"},{"groupId":"BG001","value":"3"},{"groupId":"BG002","value":"10"}]}],"title":"France"},{"categories":[{"measurements":[{"groupId":"BG000","value":"75"},{"groupId":"BG001","value":"84"},{"groupId":"BG002","value":"159"}]}],"title":"Germany"},{"categories":[{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"2"},{"groupId":"BG002","value":"2"}]}],"title":"Croatia"}],"paramType":"NUMBER","title":"Region of Enrollment","unitOfMeasure":"participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"115"},{"groupId":"BG001","value":"132"},{"groupId":"BG002","value":"247"}]}],"title":"0"},{"categories":[{"measurements":[{"groupId":"BG000","value":"183"},{"groupId":"BG001","value":"166"},{"groupId":"BG002","value":"349"}]}],"title":"1"},{"categories":[{"measurements":[{"groupId":"BG000","value":"16"},{"groupId":"BG001","value":"20"},{"groupId":"BG002","value":"36"}]}],"title":"2"},{"categories":[{"measurements":[{"groupId":"BG000","value":"1"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"1"}]}],"title":"Missing"}],"description":"Classifies participants according to their functional impairment. Scores range from 0 (Fully Active) to 5 (Death). 0 - Fully Active. 1 - Ambulatory, Restricted Strenuous Activity. 2 - Ambulatory, No Work Activities. 3 - Partially Confined to Bed, Limited Self Care. 4 - Completely Disabled. 5 - Death.","paramType":"NUMBER","title":"Eastern Cooperative Oncology Group (ECOG) Performance Status (PS) at Baseline","unitOfMeasure":"participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"26"},{"groupId":"BG001","value":"27"},{"groupId":"BG002","value":"53"}]}],"title":"Ex-Light Smoker"},{"categories":[{"measurements":[{"groupId":"BG000","value":"51"},{"groupId":"BG001","value":"53"},{"groupId":"BG002","value":"104"}]}],"title":"Nonsmoker"},{"categories":[{"measurements":[{"groupId":"BG000","value":"238"},{"groupId":"BG001","value":"238"},{"groupId":"BG002","value":"476"}]}],"title":"Smoker"}],"paramType":"NUMBER","title":"Smoking","unitOfMeasure":"participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"9"},{"groupId":"BG001","value":"11"},{"groupId":"BG002","value":"20"}]}],"title":"Stage IIIB"},{"categories":[{"measurements":[{"groupId":"BG000","value":"305"},{"groupId":"BG001","value":"307"},{"groupId":"BG002","value":"612"}]}],"title":"Stage IV"},{"categories":[{"measurements":[{"groupId":"BG000","value":"1"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"1"}]}],"title":"Missing"}],"description":"Stage means how big the tumor is and how far it has spread. Stages range from 0 (not spread) to IV (spread throughout the body). Stage IIIB - the cancer has spread to nearby tissue or spread to far away lymph nodes. Stage IV - the cancer has spread to other organs of the body such as the other lung, brain, or liver.","paramType":"NUMBER","title":"Disease Stage at Study Entry","unitOfMeasure":"participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"307"},{"groupId":"BG001","value":"311"},{"groupId":"BG002","value":"618"}]}],"title":"Adenocarcinoma/Large Cell Carcinoma"},{"categories":[{"measurements":[{"groupId":"BG000","value":"7"},{"groupId":"BG001","value":"7"},{"groupId":"BG002","value":"14"}]}],"title":"Other"},{"categories":[{"measurements":[{"groupId":"BG000","value":"1"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"1"}]}],"title":"Missing"}],"paramType":"NUMBER","title":"Disease Histology","unitOfMeasure":"participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"103"},{"groupId":"BG001","value":"109"},{"groupId":"BG002","value":"212"}]}],"title":"Bone"},{"categories":[{"measurements":[{"groupId":"BG000","value":"27"},{"groupId":"BG001","value":"25"},{"groupId":"BG002","value":"52"}]}],"title":"Brain"},{"categories":[{"measurements":[{"groupId":"BG000","value":"58"},{"groupId":"BG001","value":"64"},{"groupId":"BG002","value":"122"}]}],"title":"Liver"},{"categories":[{"measurements":[{"groupId":"BG000","value":"259"},{"groupId":"BG001","value":"268"},{"groupId":"BG002","value":"527"}]}],"title":"Lung"},{"categories":[{"measurements":[{"groupId":"BG000","value":"239"},{"groupId":"BG001","value":"240"},{"groupId":"BG002","value":"479"}]}],"title":"Lymph Nodes"},{"categories":[{"measurements":[{"groupId":"BG000","value":"21"},{"groupId":"BG001","value":"22"},{"groupId":"BG002","value":"43"}]}],"title":"Peritoneal"},{"categories":[{"measurements":[{"groupId":"BG000","value":"111"},{"groupId":"BG001","value":"111"},{"groupId":"BG002","value":"222"}]}],"title":"Pleural"},{"categories":[{"measurements":[{"groupId":"BG000","value":"7"},{"groupId":"BG001","value":"5"},{"groupId":"BG002","value":"12"}]}],"title":"Skin"},{"categories":[{"measurements":[{"groupId":"BG000","value":"19"},{"groupId":"BG001","value":"21"},{"groupId":"BG002","value":"40"}]}],"title":"Soft Tissue"},{"categories":[{"measurements":[{"groupId":"BG000","value":"87"},{"groupId":"BG001","value":"93"},{"groupId":"BG002","value":"180"}]}],"title":"Other"}],"description":"Participants may record multiple sites of metastatic disease.","paramType":"NUMBER","title":"Sites of Metastatic Disease","unitOfMeasure":"participants"}]}