{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.23626","value":"-0.0053"},{"groupId":"OG001","spread":"0.23866","value":"-0.0083"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"305"},{"groupId":"OG001","value":"245"}],"units":"Participants"}],"description":"The EQ-5D is a generic, multidimensional, health-related, quality-of-life instrument. The profile allows participants to rate their health state in 5 health domains: mobility, self-care, usual activities, pain/discomfort, and anxiety/depression using a three level scale 1-3 (no problem, some problems, and major problems). These combinations of attributes were converted into a weighted health-state Index Score according to the United Kingdom (UK) population-based algorithm. The possible values for the Index Score ranged from -0.59 (severe problems in all 5 dimensions) to 1.0 (no problem in any dimension).","dispersionType":"Standard Deviation","groups":[{"description":"Necitumumab + Gemcitabine + Cisplatin\n\nNecitumumab: 800 mg I.V. infusion on Days 1 and 8 of every 3 week cycle.\n\nContinues until progressive disease, toxicity, noncompliance, or withdrawal.\n\nGemcitabine: 1250 mg/m2 on Days 1 and 8 of every 3 week cycle.\n\nContinues for a maximum of six cycles.\n\nCisplatin: 75 mg/m2 IV on Day 1 of every 3 week cycle.\n\nContinues for a maximum of six cycles.","id":"OG000","title":"Necitumumab + Gemcitabine + Cisplatin"},{"description":"Gemcitabine + Cisplatin\n\nGemcitabine: 1250 mg/m2 on Days 1 and 8 of every 3 week cycle.\n\nContinues for a maximum of six cycles.\n\nCisplatin: 75 mg/m2 IV on Day 1 of every 3 week cycle.\n\nContinues for a maximum of six cycles.","id":"OG001","title":"Gemcitabine + Cisplatin"}],"paramType":"MEAN","populationDescription":"All randomized participants who had evaluable baseline and postbaseline EQ-5D data.","reportingStatus":"POSTED","timeFrame":"Baseline, Cycle 6 (Cycle = 3 Weeks)","title":"Mean Change From Baseline in Patient Reported Outcomes (PRO) Using the European Quality of Life-5 Dimension (EQ-5D)","type":"SECONDARY","unitOfMeasure":"units on a scale"}