{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"22"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"33"}],"units":"Participants"}],"description":"Overall Response = Complete Response + Near Complete Response + Very Good Partial Response + Partial Response + Minor Response Complete Response: resolution of all symptoms, normalization of serum IgM levels with complete disappearance of IgM paraprotein by immunofixation, and resolution of any adenopathy or splenomegaly. A near CR (nCR) is defined as fulfilling all CR criteria in the presence of positive immunofixation test for an IgM paraprotein.\n\nVery Good Partial Response: \\> 90% reduction in serum IgM levels. Partial Response: \\> 50% reduction in serum IgM levels. Minor Response: 25-49% reduction in serum IgM levels Progressive Disease: greater than 25% increase in serum IgM level occurs from the lowest attained response value or progression of clinically significant disease related symptom(s).\n\nStable Disease: \\< 25% change in serum IgM levels, in the absence of new or increasing adenopathy or splenomegaly and/or other progressive signs or symptoms of WM","groups":[{"description":"RAD001, oral, 10 mg, daily\n\nRAD001 : Taken orally once a day","id":"OG000","title":"RAD001"}],"paramType":"NUMBER","reportingStatus":"POSTED","timeFrame":"End of Treatment, an average of 16 months","title":"Overall Response Rate of RAD001 in Patients With Previously Untreated WM","type":"PRIMARY","unitOfMeasure":"participants"}