{"denoms":[{"counts":[{"groupId":"BG000","value":"41"},{"groupId":"BG001","value":"23"},{"groupId":"BG002","value":"64"}],"units":"Participants"}],"groups":[{"description":"First Cycle High-dose (HD) chemotherapy followed by stem-cell infusion (PBPC)\n\nYou will receive 1 dose of Outpatient IV at Bevacizumab 7.5mg/kg.\n\nHD Cycle #1: Gemcitabine/Docetaxel/Melphalan/Carboplatin + PBPC\n\nGemcitabine: 1800 mg/m\\^2 IV over 3 hours on Days -5 to Day -2.\n\nDocetaxel: Docetaxel 300 mg/m\\^2 IV over 2 hours on Day -5.\n\nMelphalan: 50 mg/m\\^2 IV over 15 minutes on Days -4 to Day -2.\n\nCarboplatin: Cycle 1: 333 mg/m\\^2 IV over 2 hours on Days -4 to -2.\n\nStem Cell Transplant: Stem cell infusion on Day 0.\n\nSecond Cycle High-dose (HD) chemotherapy followed by stem-cell infusion (PBPC)\n\nHD Cycle #2: Ifosfamide/Carboplatin/Etoposide + PBPC\n\nCarboplatin: Cycle 1: 333 mg/m\\^2 IV over 2 hours on Days -4 to -2.\n\nCycle #2: 300 mg/m\\^2 IV over 2 hours on Days -6 to -3.\n\nMesna: 3,000 mg/m\\^2 per day in 96-hour continuous infusion, starting 30 minutes prior to the first dose of ifosfamide, on Days -6 to -4.\n\nIfosfamide: 3,000 mg/m\\^2 IV over 6 hours on Days -6 to -3\n\nEtoposide: 200 mg/m\\^2 IV over 3 hours, every 12 hours on Days -6 to -4.\n\nStem Cell Transplant: Stem cell infusion on Day 0.","id":"BG000","title":"Cohort 1: HD GeM-DMC+ ICE + Bevacizumab for Refractory GCT"},{"description":"First Cycle High-dose (HD) chemotherapy followed by stem-cell infusion (PBPC)\n\nHD Cycle #1: Gemcitabine/Docetaxel/Melphalan/Carboplatin + PBPC\n\nGemcitabine: 1800 mg/m\\^2 IV over 3 hours on Days -5 to Day -2.\n\nDocetaxel: Docetaxel 300 mg/m\\^2 IV over 2 hours on Day -5.\n\nMelphalan: 50 mg/m\\^2 IV over 15 minutes on Days -4 to Day -2.\n\nCarboplatin: Cycle 1: 333 mg/m\\^2 IV over 2 hours on Days -4 to -2.\n\nStem Cell Transplant: Stem cell infusion on Day 0.\n\nSecond Cycle High-dose (HD) chemotherapy followed by stem-cell infusion (PBPC)\n\nHD Cycle #2: Ifosfamide/Carboplatin/Etoposide + PBPC\n\nCarboplatin: Cycle 1: 333 mg/m\\^2 IV over 2 hours on Days -4 to -2.\n\nCycle #2: 300 mg/m\\^2 IV over 2 hours on Days -6 to -3.\n\nMesna: 3,000 mg/m\\^2 per day in 96-hour continuous infusion, starting 30 minutes prior to the first dose of ifosfamide, on Days -6 to -4.\n\nIfosfamide: 3,000 mg/m\\^2 IV over 6 hours on Days -6 to -3\n\nEtoposide: 200 mg/m\\^2 IV over 3 hours, every 12 hours on Days -6 to -4.\n\nStem Cell Transplant: Stem cell infusion on Day 0.","id":"BG001","title":"Cohort 2: HD GeM-DMC+ ICE for Refractory GCT"},{"description":"Total of all reporting groups","id":"BG002","title":"Total"}],"measures":[{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"2"},{"groupId":"BG001","value":"1"},{"groupId":"BG002","value":"3"}],"title":"<=18 years"},{"measurements":[{"groupId":"BG000","value":"39"},{"groupId":"BG001","value":"22"},{"groupId":"BG002","value":"61"}],"title":"Between 18 and 65 years"},{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"0"}],"title":">=65 years"}]}],"paramType":"COUNT_OF_PARTICIPANTS","title":"Age, Categorical","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"3"},{"groupId":"BG001","value":"2"},{"groupId":"BG002","value":"5"}],"title":"Female"},{"measurements":[{"groupId":"BG000","value":"38"},{"groupId":"BG001","value":"21"},{"groupId":"BG002","value":"59"}],"title":"Male"}]}],"paramType":"COUNT_OF_PARTICIPANTS","title":"Sex: Female, Male","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"18"},{"groupId":"BG001","value":"12"},{"groupId":"BG002","value":"30"}],"title":"Hispanic or Latino"},{"measurements":[{"groupId":"BG000","value":"20"},{"groupId":"BG001","value":"11"},{"groupId":"BG002","value":"31"}],"title":"Not Hispanic or Latino"},{"measurements":[{"groupId":"BG000","value":"3"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"3"}],"title":"Unknown or Not Reported"}]}],"paramType":"COUNT_OF_PARTICIPANTS","title":"Ethnicity (NIH/OMB)","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"41"},{"groupId":"BG001","value":"23"},{"groupId":"BG002","value":"64"}]}],"title":"United States"}],"paramType":"NUMBER","title":"Region of Enrollment","unitOfMeasure":"participants"}]}