{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"41.8","upperLimit":"2.3","value":"1"},{"groupId":"OG001","lowerLimit":"47.9","upperLimit":"1.9","value":"1"},{"groupId":"OG002","value":"2"},{"groupId":"OG003","value":"1"},{"groupId":"OG004","value":"2"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"0"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"0"}]}],"title":"Postbaseline Grade 0"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"10"},{"groupId":"OG002","value":"9"},{"groupId":"OG003","value":"2"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"1"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"0"}]}],"title":"Postbaseline Grade 1"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"8"},{"groupId":"OG003","value":"8"},{"groupId":"OG004","value":"1"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"0"},{"groupId":"OG007","value":"4"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"0"}]}],"title":"Postbaseline Grade 2"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"6"},{"groupId":"OG002","value":"19"},{"groupId":"OG003","value":"28"},{"groupId":"OG004","value":"2"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"0"},{"groupId":"OG007","value":"4"},{"groupId":"OG008","value":"8"},{"groupId":"OG009","value":"3"}]}],"title":"Postbaseline Grade 3"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"17"},{"groupId":"OG003","value":"20"},{"groupId":"OG004","value":"3"},{"groupId":"OG005","value":"2"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"19"},{"groupId":"OG008","value":"24"},{"groupId":"OG009","value":"4"}]}],"title":"Postbaseline Missing"}],"denoms":[{"counts":[{"groupId":"OG000","value":"146"},{"groupId":"OG001","value":"146"},{"groupId":"OG002","value":"146"},{"groupId":"OG003","value":"146"},{"groupId":"OG004","value":"146"},{"groupId":"OG005","value":"73"},{"groupId":"OG006","value":"73"},{"groupId":"OG007","value":"73"},{"groupId":"OG008","value":"73"},{"groupId":"OG009","value":"73"}],"units":"Participants"}],"description":"Shift table from baseline to last available postbaseline fibrosis grade by treatment\n\nThe grade gives an indication of the activity or amount of inflammation and the stage represents the amount of fibrosis or scarring. The grade is assigned a number based on the degree of inflammation, which is usually scored from 0-4 with 0 being no activity and 3 or 4 considered severe activity","groups":[{"description":"5 milligram tablets administered orally in an outpatient setting according to the protocol-specified dosing schedule","id":"OG000","title":"Ruxolitinib"},{"id":"OG001","title":"Ruxolitinib - Grade 1"},{"id":"OG002","title":"Ruxolitinib - Grade 2"},{"id":"OG003","title":"Ruxolitinib - Grade 3"},{"id":"OG004","title":"Ruxolitinib - Missing"},{"id":"OG005","title":"Best Available Therapy (BAT) - Grade 0"},{"id":"OG006","title":"Best Available Therapy (BAT) - Grade 1"},{"id":"OG007","title":"Best Available Therapy (BAT) - Grade 2"},{"id":"OG008","title":"Best Available Therapy (BAT) - Grade 3"},{"id":"OG009","title":"Best Available Therapy - Missing"}],"paramType":"NUMBER","populationDescription":"Full Analysis Set (FAS)\n\nNumbers of Participants Analyzed reflect only those participants who were randomized to either Ruxolitinib or Best Available Therapy and do not count those participants who could have crossed over to Ruxolitinib","reportingStatus":"POSTED","timeFrame":"Baseline, once a year","title":"Bone Marrow Histomorphology","type":"SECONDARY","unitOfMeasure":"participants"}