{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"33"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"35"}],"units":"Participants"}],"description":"Number of patients achieving at least a partial response or better in disease status at Day 100 post-transplant, as defined by the International Myeloma Working Group (IMWG) disease response criteria. Partial response in disease status is defined by the IMWG as ≥50% reduction of serum M-protein and reduction in 24-h urinary M-protein by ≥90% or to \\<200 mg per 24 hours; If the serum and urine M-protein are unmeasurable, a ≥50% decrease in the difference between involved and uninvolved FLC levels is required in place of the M-protein criteria; If serum and urine M-protein are unmeasurable, and serum-free light assay is also unmeasurable, ≥50% reduction in plasma cells is required in place of M-protein, provided baseline bone marrow plasma-cell percentage was ≥30%. In addition to these criteria, if present at baseline, a ≥50% reduction in the size (SPD) of soft tissue plasmacytomas is also required","groups":[{"description":"Bendamustine 225 mg/m\\^2 total, Melphalan 200 mg/m\\^2 total (140 mg/m\\^2 total for patients with Creatinine Clearance \\<70 ml/min)\n\nMelphalan: 100 mg/m\\^2 for 2 days (70 mg/m\\^2 for patients with Creatinine Clearance \\<70 ml/min)\n\nBendamustine: 125 mg/m\\^2 given on the 1st day of melphalan and 100mg/m\\^2 given on the 2nd day of melphalan","id":"OG000","title":"Phase 2"}],"paramType":"COUNT_OF_PARTICIPANTS","populationDescription":"Phase 2 includes all patients treated on phase 2 of the study (28 patients), and patients treated at Dose Level 6 of the Phase 1 portion of the study (7 patients). The dose level used during Phase 2 was Dose Level 6.","reportingStatus":"POSTED","timeFrame":"100 days post-transplant","title":"Overall Response Rate (Phase 2) - Number of Participants Achieving at Least a Partial Response or Better in Disease Status at Day 100 Post-transplant","type":"PRIMARY","unitOfMeasure":"Participants"}