{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"1.62"},{"groupId":"OG001","value":"1.71"},{"groupId":"OG002","value":"0.78"},{"groupId":"OG003","value":"0.96"},{"groupId":"OG004","value":"1.32"},{"groupId":"OG005","value":"1.08"},{"groupId":"OG006","value":"1.00"},{"groupId":"OG007","value":"0.92"},{"groupId":"OG008","value":"1.49"},{"groupId":"OG009","value":"1.05"},{"groupId":"OG010","value":"1.16"},{"groupId":"OG011","value":"1.03"},{"groupId":"OG012","value":"1.22"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"1"},{"groupId":"OG001","value":"1"},{"groupId":"OG002","value":"1"},{"groupId":"OG003","value":"1"},{"groupId":"OG004","value":"1"},{"groupId":"OG005","value":"1"},{"groupId":"OG006","value":"1"},{"groupId":"OG007","value":"1"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"1"},{"groupId":"OG010","value":"1"},{"groupId":"OG011","value":"1"},{"groupId":"OG012","value":"1"}],"units":"Participants"}],"description":"Patients diagnosed with early stage (asymptomatic) CLL were supplemented with escalating doses of omega-3 (n-3) fatty acids (2.4 g of n-3/day up to 7.2 g of n-3/day). Given that these patients are asymptomatic and did not require treatment, measures of tumor mass during and after omega-3 supplementation, as evaluated by standard clinical tests of disease activity, were not performed. Instead, absolute lymphocyte counts (ALC), as a measure of tumor burden, was evaluated before and after omega-3 supplementation. Data represents the fold change in ALC post omega-3 consumption as compared to baseline ALC.\n\nPatients with MGUS or SMM were not enrolled into this study.","groups":[{"description":"Fold change in ALC after omega-3 consumption as compared to baseline ALC.","id":"OG000","title":"Fold Change in ALC-Patient 1"},{"description":"Fold change in ALC after omega-3 consumption as compared to baseline ALC.","id":"OG001","title":"Fold Change in ALC-Patient 2"},{"description":"Fold change in ALC after omega-3 consumption as compared to baseline ALC.","id":"OG002","title":"Fold Change in ALC-Patient 3"},{"description":"Fold change in ALC after omega-3 consumption as compared to baseline ALC.","id":"OG003","title":"Fold Change in ALC-Patient 4"},{"description":"Fold change in ALC after omega-3 consumption as compared to baseline ALC.","id":"OG004","title":"Fold Change in ALC-Patient 5"},{"description":"Fold change in ALC after omega-3 consumption as compared to baseline ALC.","id":"OG005","title":"Fold Change in ALC-Patient 6"},{"description":"Fold change in ALC after omega-3 consumption as compared to baseline ALC.","id":"OG006","title":"Fold Change in ALC-Patient 7"},{"description":"Fold change in ALC after omega-3 consumption as compared to baseline ALC.","id":"OG007","title":"Fold Change in ALC-Patient 8"},{"description":"Fold change in ALC after omega-3 consumption as compared to baseline ALC.","id":"OG008","title":"Fold Change in ALC-Patient 9"},{"description":"Fold change in ALC after omega-3 consumption as compared to baseline ALC.","id":"OG009","title":"Fold Change in ALC-Patient 10"},{"description":"Fold change in ALC after omega-3 consumption as compared to baseline ALC.","id":"OG010","title":"Fold Change in ALC-Patient 11"},{"description":"Fold change in ALC after omega-3 consumption as compared to baseline ALC.","id":"OG011","title":"Fold Change in ALC-Patient 13"},{"description":"Fold change in ALC after omega-3 consumption as compared to baseline ALC.","id":"OG012","title":"Fold Change in ALC-Patient 14"}],"paramType":"NUMBER","populationDescription":"Patients who's absolute lymphocyte counts were known prior to omega-3 initiation (baseline) and after omega-3 consumption were included in this analysis. Patients who's ALC was unknown prior to omega-3 initiation or after omega-3 consumption were excluded.","reportingStatus":"POSTED","timeFrame":"Baseline, month 1, month 2, month 3, month 6, month 9, 12 months","title":"The Degree of Change in Tumor Mass Measurements During and After Omega-3 Supplementation as Evaluated by Standard Clinical Tests of Disease Activity.","type":"PRIMARY","unitOfMeasure":"Fold Change"}