{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"4.17","upperLimit":"5.68","value":"4.53"},{"groupId":"OG001","lowerLimit":"3.58","upperLimit":"5.85","value":"4.40"}]}],"title":"Deterioration global health status score ≥ 5%"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"4.17","upperLimit":"6.97","value":"4.83"},{"groupId":"OG001","lowerLimit":"2.83","upperLimit":"7.00","value":"4.37"}]}],"title":"Deterioration in PF domain score of ≥ 5%"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"5.55","upperLimit":"8.41","value":"6.93"},{"groupId":"OG001","lowerLimit":"4.17","upperLimit":"7.36","value":"6.93"}]}],"title":"Deterioration in EF domain score of ≥ 5%"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"6.93","upperLimit":"10.87","value":"8.34"},{"comment":"NA: Median time to definitive deterioration computed using Kaplan-Meier method.95% CIs calculated using Brookmeyer \\& Crowley (1982) method. Therefore, upper boundary of 95% CI may not be estimable when median is close to the longest patient follow-up","groupId":"OG001","lowerLimit":"5.62","upperLimit":"NA","value":"7.03"}]}],"title":"Deterioration in SF domain score of ≥ 5%"}],"denoms":[{"counts":[{"groupId":"OG000","value":"485"},{"groupId":"OG001","value":"239"}],"units":"Participants"}],"description":"The QLQ-C30 is composed of both multi-item scales and single-item measures. These include 5 functional scales, 3 symptom scales, a global health status - QoL scale, and 6 single items. Each of the multi-item scales includes a different set of items - no item occurs in more than 1 scale. All of the scales measures range in score from 0 to 100. A high scale score = higher response level. Thus a high score for a functional scale represents a healthy level of function, a high score for the global health status / QoL represents a high quality of life but a high score for a symptom scale / item represents a high level of symptomatology / problems. The principle for scoring these scales: 1.) Estimate the average of the items that contribute to the scale = raw score. 2.) Linear transformation to standardize the raw score, so that scores range from 0 to 100; a higher score represents a higher (\"better\") level of functioning, or a higher (\"worse\") level of symptoms.","dispersionType":"95% Confidence Interval","groups":[{"description":"Everolimus 10 mg daily in combination with exemestane 25 mg daily","id":"OG000","title":"Everolimus + Exemestane"},{"description":"Placebo of everolimus in combination with exemestane 25 mg daily","id":"OG001","title":"Placebo + Exemestane"}],"paramType":"MEDIAN","populationDescription":"All randomized patients were included in the Full Analysis Set.","reportingStatus":"POSTED","timeFrame":"Up to 21 months","title":"Patient-reported Outcomes (PROs): Time to Deterioration of PRO Scores Using Kaplan Meier - EORTC QLQ-C30","type":"SECONDARY","unitOfMeasure":"Months"}