{"groups":[{"description":"Patients receive paclitaxel (pac) IV over 60 minutes once weekly in weeks 1-12. Patients then receive dose-dense doxorubicin hydrochloride IV over 5-10 minutes and cyclophosphamide IV over 5-30 minutes (ddAC) once in weeks 13, 15, 17, and 19.\n\ndoxorubicin hydrochloride: Given IV\n\npaclitaxel: Given IV\n\ncyclophosphamide: Given IV","id":"FG000","title":"Arm 1 (Pac --> ddAC)"},{"description":"Patients receive pac and ddAC as in arm 1. Patients also receive bevacizumab (bev) IV over 30-90 minutes in weeks 1, 3, 5, 7, 9, 11, 13, 15, and 17.\n\ndoxorubicin hydrochloride: Given IV\n\npaclitaxel: Given IV\n\ncyclophosphamide: Given IV\n\nbevacizumab: Given IV","id":"FG001","title":"Arm 2 (Pac + Bev --> ddAC + Bev)"},{"description":"Patients receive pac and ddAC as in arm 1. Patients also receive carboplatin IV over 30 minutes once in weeks 1, 4, 7, and 10.\n\ndoxorubicin hydrochloride: Given IV\n\npaclitaxel: Given IV\n\ncyclophosphamide: Given IV\n\ncarboplatin: Given IV","id":"FG002","title":"Arm 3 (Pac + Carboplatin --> ddAC)"},{"description":"Patients receive pac and ddAC as in arm 1, bev as in arm 2, and carboplatin as in arm 3.\n\ndoxorubicin hydrochloride: Given IV\n\npaclitaxel: Given IV\n\ncyclophosphamide: Given IV\n\nbevacizumab: Given IV\n\ncarboplatin: Given IV","id":"FG003","title":"Arm 4 (Pac + Carboplatin + Bev --> ddAC + Bev)"}],"periods":[{"dropWithdraws":[{"reasons":[{"groupId":"FG000","numSubjects":"7"},{"groupId":"FG001","numSubjects":"3"},{"groupId":"FG002","numSubjects":"0"},{"groupId":"FG003","numSubjects":"1"}],"type":"Never Began Treatment"}],"milestones":[{"achievements":[{"groupId":"FG000","numSubjects":"115"},{"groupId":"FG001","numSubjects":"113"},{"groupId":"FG002","numSubjects":"113"},{"groupId":"FG003","numSubjects":"113"}],"type":"STARTED"},{"achievements":[{"groupId":"FG000","numSubjects":"108"},{"groupId":"FG001","numSubjects":"110"},{"groupId":"FG002","numSubjects":"113"},{"groupId":"FG003","numSubjects":"112"}],"type":"COMPLETED"},{"achievements":[{"groupId":"FG000","numSubjects":"7"},{"groupId":"FG001","numSubjects":"3"},{"groupId":"FG002","numSubjects":"0"},{"groupId":"FG003","numSubjects":"1"}],"type":"NOT COMPLETED"}],"title":"Overall Study"}]}