{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"98.6","upperLimit":"100","value":"100"},{"groupId":"OG001","lowerLimit":"82.4","upperLimit":"97.9","value":"93"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"270"},{"groupId":"OG001","value":"55"}],"units":"Participants"}],"description":"Complete Response (CR) is a complete disappearance of all disease with the exception of the following. If no PET scan or when the PET scan was positive before therapy, a post-treatment residual mass of any size is permitted if it is PET negative. If the PET scan was negative before therapy, all nodal masses at baseline must have regressed. No new lesions. Previously enlarged organs must have regressed and not be palpable. Bone marrow (BM) must be negative if positive at baseline. Normalization of markers. Partial Response (PR) is a 50% decrease in the sum of products of greatest diameters (SPD) for up to 6 identified dominant lesions, including spleenic and hepatic nodules from baseline. No new lesions and no increase in the size of liver, spleen or other nodes. If PET scan or when the PET scan was positive before therapy, PET should be positive in at least one previously involved site.","dispersionType":"95% Confidence Interval","groups":[{"description":"Initial ABVD: Doxorubicin 25 mg/m\\^2 IV, Bleomycin 10u/m\\^2 IV, Vinblastine 6mg/m\\^2 IV, Dacarbazine 375 mg/m\\^2 IV Days 1,15 Q 28 Days x 2 cycles Continued ABVD: Doxorubicin 25 mg/m\\^2 IV, Bleomycin 10u/m\\^2 IV, Vinblastine 6mg/m\\^2 IV, Dacarbazine 375 mg/m\\^2 IV Days 1,15 Q 28 Days x 4 cycles","id":"OG000","title":"PET-negative: Continued ABVD After 2 Cycles of ABVD"},{"description":"Initial ABVD: Doxorubicin 25 mg/m\\^2 IV, Bleomycin 10u/m\\^2 IV, Vinblastine 6mg/m\\^2 IV, Dacarbazine 375 mg/m\\^2 IV Days 1,15 Q 28 Days x 2 cycles escalated BEACOPP: Etoposide 200 mg/m\\^2 IV Days 1, 2, 3, Doxorubicin 35 mg/m\\^2 IV Day 1, Cyclophosphamide 1,250 mg/m\\^2 IV Day 1, Procarbzine 100 mg/m\\^2 PO Days 1-7, Prednisone 40 mg/m\\^2 PO Days 1-14, Bleomycin 10u/m\\^2 IV Day 8, Vincristine 1.4 mg/m\\^2 IV Day 8, G-CSF 5mcg/kg/day SQ Days 8-14, Q 21 Days x 6 cycles","id":"OG001","title":"PET-positive: BEACOPP Escalated After 2 Cycles of ABVD"}],"paramType":"NUMBER","populationDescription":"Only eligible and evaluable HIV-negative patients who treated with response-adapted therapy based on FDG-PET imaging after 2 cycles of ABVD were included in the analysis","reportingStatus":"POSTED","timeFrame":"7 months after registration","title":"Complete and Partial Response Rates for HIV-negative Patients Treated With Response- Adapted Therapy Based on FDG-PET Imaging After 2 Cycles of ABVD","type":"SECONDARY","unitOfMeasure":"percentage of patients"}