{"analyses":[{"groupDescription":"18% n=9 of the patients vomited compared to the FHCRC historic rate of 28%. p=0.03. PMID: 21372706 reference for historical data at FHCRC.","groupIds":["OG000"],"nonInferiorityType":"SUPERIORITY_OR_OTHER","pValue":"0.03","statisticalMethod":"t-test, 1 sided"},{"groupDescription":"Twelve patients (24%) had a greater than two-point increase in MAT score for nausea from baseline by the end of their infusion. That rate compares to the FHCRC historic rate of 58% (p \\<0.0001). PMID: 21372706 reference for historical data at FHCRC","groupIds":["OG000"],"nonInferiorityType":"SUPERIORITY_OR_OTHER","pValue":"<0.0001","statisticalMethod":"t-test, 1 sided"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"23"}]}],"title":"MAT score >2 on arrival and pre-ondansetron"},{"categories":[{"measurements":[{"groupId":"OG000","value":"9"}]}],"title":"Baseline MAT score >2 prior to first ASCT infusion"},{"categories":[{"measurements":[{"groupId":"OG000","value":"12"}]}],"title":"MAT score increases >2 by end of infusion"},{"categories":[{"measurements":[{"groupId":"OG000","value":"9"}]}],"title":"Number of patients that vomited"}],"denoms":[{"counts":[{"groupId":"OG000","value":"49"}],"units":"Participants"}],"description":"Nausea Multinational Association of Supportive Care in Cancer Antiemesis Tool™ (MAT). Increased MAT scores represent worse outcome (score 0-10). Vomiting represented as present or absent.","groups":[{"description":"Patients receive 16mg ondansetron IV once 30-60 minutes before undergoing autologous peripheral blood stem cell transplantation.\n\nondansetron: Given IV\n\nsurvey administration: Correlative studies\n\nmanagement of therapy complications: Ondansetron IV","id":"OG000","title":"Ondansetron Therapy"}],"paramType":"COUNT_OF_PARTICIPANTS","reportingStatus":"POSTED","timeFrame":"Baseline up to 120 minutes","title":"Reduction in Rates of Nausea or Vomiting After Ondansetron (Compared to FHCRC Historical Rates)","type":"PRIMARY","unitOfMeasure":"Participants"}