{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"14.4","upperLimit":"34.8","value":"21.8"},{"groupId":"OG001","lowerLimit":"7.9","upperLimit":"9.4","value":"8.4"},{"groupId":"OG002","lowerLimit":"25.4","upperLimit":"25.4","value":"25.4"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"12"},{"groupId":"OG001","value":"6"},{"groupId":"OG002","value":"1"}],"units":"Participants"}],"description":"Duration of response was defined as time between the onset of response and disease progression in months, among patients treated at the recommended phase II dose who experienced a response to treatment. Per criteria of the International Myeloma Working Group, progressive disease was defined as one of the following: increase of 25% from best confirmed response in serum M-component, urine M-component, free light chain (FLC), bone marrow plasma cell percentage, or development of new or increase in size of bone lesions or soft tissue plasma cytomas. Development of hypercalcemia that can be attributed solely to the myeloma also constituted progression.","dispersionType":"Inter-Quartile Range","groups":[{"description":"Lenalidomide 25 mg/day days 1-21 and Dexamethasone 40 mg days 1, 8, 15 and 22 every 28 days.","id":"OG000","title":"Group A=30-60 CrCl (mL/Min)"},{"description":"Lenalidomide 25 mg/day days 1-21 and Dexamethasone 40 mg days 1, 8, 15 and 22 every 28 days.","id":"OG001","title":"Group B=CrCL<30 mL/Min Not on Dialysis"},{"description":"Lenalidomide 25 mg/day days 1-21 and Dexamethasone 40 mg days 1, 8, 15 and 22 every 28 days. Dialysis includes hemodialysis or peritoneal dialysis. When lenalidomide and/or dexamethasone treatment occurs on a dialysis day, lenalidomide and/or dexamethasone must be taken after dialysis.","id":"OG002","title":"Group C=CrCL<30 mL/Min and on Dialysis"}],"paramType":"MEDIAN","populationDescription":"Patients treated at the recommended phase II dose who experienced a response to treatment","reportingStatus":"POSTED","timeFrame":"56 months","title":"Duration of Response","type":"SECONDARY","unitOfMeasure":"Months"}