{"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"0"},{"groupId":"OG002","value":"0"}],"units":"Participants"}],"groups":[{"description":"Patients receive oral varenicline once daily on days 1-3 and twice daily thereafter for a total of 6 months or when a comfortable level of smoking abstinence is reached.\n\nvarenicline: Given orally","id":"OG000","title":"Arm I"},{"description":"Patients receive oral varenicline placebo once daily on days 1-3 and twice daily thereafter for a total of 6 months or when a comfortable level of smoking abstinence is reached.\n\nplacebo: Given orally","id":"OG001","title":"Arm II"},{"description":"Patients receive a nicotine patch, with doses tapering over time for a total of 26 weeks. Patients also receive nicotine gum to quell breakthrough urges. Patients may stop treatment when a comfortable level of smoking abstinence is reached.\n\nnicotine: Given transdermally and orally","id":"OG002","title":"Arm III"}],"populationDescription":"Data not collected","reportingStatus":"POSTED","timeFrame":"12 months","title":"Retention in Methadone Maintenance","type":"SECONDARY"}