{"description":"The limited number of patients limited our ability to analyze groups separately for adverse event reporting. As a result, adverse events were collected irrespective of dose and therefore cannot be separated further.","eventGroups":[{"description":"Bortezomib was dose escalated at 1, 1.3, and 1.6 mg/m2 (3 × 3 design) on days -4 and -1 before transplantation with melphalan 200 mg/m2 given on day -2.","id":"EG000","otherNumAffected":12,"otherNumAtRisk":12,"seriousNumAffected":6,"seriousNumAtRisk":12,"title":"Phase I Cohort"},{"description":"Bortezomib 1.6 mg/m2 (3 × 3 design) on days -4 and -1 before transplantation with melphalan 200 mg/m2 given on day -2.","id":"EG001","otherNumAffected":20,"otherNumAtRisk":20,"seriousNumAffected":6,"seriousNumAtRisk":20,"title":"Phase II Cohort"}],"frequencyThreshold":"0","otherEvents":[{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Cardiac disorders","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":12},{"groupId":"EG001","numAffected":0,"numAtRisk":20}],"term":"Hypotension"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Cardiac 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disorders","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":12},{"groupId":"EG001","numAffected":1,"numAtRisk":20}],"term":"Pulmonary Embolus"}]}