{"classes":[{"categories":[{"measurements":[{"comment":"NA = many patients were censored at the time of last assessment, and therefore upper bound was not estimable- confidence intervals are extremely wide.","groupId":"OG000","lowerLimit":"14.3","upperLimit":"NA","value":"19.8"},{"comment":"NA = many patients were censored at the time of last assessment, and therefore upper bound was not estimable- confidence intervals are extremely wide.","groupId":"OG001","lowerLimit":"14.6","upperLimit":"NA","value":"27.9"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"24"},{"groupId":"OG001","value":"20"}],"units":"Participants"}],"description":"Duration of response is measured from date of first confirmed response until date of disease progression.","dispersionType":"95% Confidence Interval","groups":[{"description":"Bortezomib 1.3 mg/m2 is administered intravenously in a 3-5 second bolus on days 1, 4, 8, and 11 of a 28 day cycle. Six cycles are planned. On days when both melphalan and bortezomib are given, melphalan is given at least one hour prior to bortezomib. Melphalan 6 mg/m2 is administered orally on an empty stomach daily on days 1-7 of each cycle. Prednisone 60 mg/m2 is administered orally daily on days 1-7 of each cycle. Patients did not proceed to autologous stem cell transplant (ASCT).","id":"OG000","title":"Bortezomib+Melphalan+Prednisone: Non-ASCT"},{"description":"Bortezomib 1.3 mg/m2 is administered intravenously in a 3-5 second bolus on days 1, 4, 8, and 11 of a 28 day cycle. Six cycles are planned. On days when both melphalan and bortezomib are given, melphalan is given at least one hour prior to bortezomib. Melphalan 6 mg/m2 is administered orally on an empty stomach daily on days 1-7 of each cycle. Prednisone 60 mg/m2 is administered orally daily on days 1-7 of each cycle. Patients proceeded to autologous stem cell transplant (ASCT).","id":"OG001","title":"Bortezomib+Melphalan+Prednisone: ASCT"}],"paramType":"MEDIAN","reportingStatus":"POSTED","timeFrame":"up to 4 years","title":"Median Duration of Response","type":"SECONDARY","unitOfMeasure":"months"}