{"eventGroups":[{"description":"Dexamethasone 40 mg PO on days 1, 8, 15, 22","id":"EG000","otherNumAffected":21,"otherNumAtRisk":21,"seriousNumAffected":7,"seriousNumAtRisk":21,"title":"Treatment"}],"frequencyThreshold":"0","otherEvents":[{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":18,"numAtRisk":21,"numEvents":105}],"term":"Hemoglobin decreased"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Cardiac disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Cardiac pain"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Gastrointestinal disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":21,"numEvents":2}],"term":"Abdominal pain"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Gastrointestinal disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":3,"numAtRisk":21,"numEvents":3}],"term":"Constipation"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Gastrointestinal disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":8,"numAtRisk":21,"numEvents":15}],"term":"Diarrhea"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Gastrointestinal disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":5}],"term":"Gastritis"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Gastrointestinal disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":3,"numAtRisk":21,"numEvents":3}],"term":"Nausea"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Gastrointestinal disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Vomiting"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"General disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":20,"numAtRisk":21,"numEvents":111}],"term":"Fatigue"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"General disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Fever"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Immune system disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Hypersensitivity"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Infections and infestations","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Infectious colitis"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Infections and infestations","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Pneumonia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Infections and infestations","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":21,"numEvents":3}],"term":"Skin infection"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Infections and infestations","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":2}],"term":"Upper respiratory infection"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Investigations","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":17,"numAtRisk":21,"numEvents":63}],"term":"Leukocyte count decreased"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Investigations","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":4}],"term":"Lymphocyte count decreased"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Investigations","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":12,"numAtRisk":21,"numEvents":33}],"term":"Neutrophil count decreased"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Investigations","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":14,"numAtRisk":21,"numEvents":66}],"term":"Platelet count decreased"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Metabolism and nutrition disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Anorexia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Metabolism and nutrition disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Blood glucose increased"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Metabolism and nutrition disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Serum potassium increased"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Metabolism and nutrition disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Tumor lysis syndrome"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Musculoskeletal and connective tissue disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Arthritis"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Musculoskeletal and connective tissue disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Back pain"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Musculoskeletal and connective tissue disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Myalgia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Nervous system disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Peripheral motor neuropathy"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Nervous system disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":17,"numAtRisk":21,"numEvents":97}],"term":"Peripheral sensory neuropathy"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Nervous system disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Taste alteration"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Psychiatric disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":21,"numEvents":8}],"term":"Agitation"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Psychiatric disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":3,"numAtRisk":21,"numEvents":4}],"term":"Anxiety"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Psychiatric disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Depression"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Psychiatric disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":9}],"term":"Insomnia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Renal and urinary disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Cystitis"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Respiratory, thoracic and mediastinal disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":3,"numAtRisk":21,"numEvents":3}],"term":"Dyspnea"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Respiratory, thoracic and mediastinal disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Pleural effusion"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Vascular disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Hypotension"}],"seriousEvents":[{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Hemoglobin decreased"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Cardiac disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Left ventricular failure"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Cardiac disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Restrictive cardiomyopathy"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Gastrointestinal disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Abdominal pain"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Infections and infestations","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Appendicitis"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Infections and infestations","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Encephalomyelitis infection"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Investigations","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":3,"numAtRisk":21,"numEvents":4}],"term":"Leukocyte count decreased"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Investigations","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":21,"numEvents":3}],"term":"Platelet count decreased"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Nervous system disorders","sourceVocabulary":"MedDRA 10","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":21,"numEvents":1}],"term":"Peripheral sensory neuropathy"}]}