{"denoms":[{"counts":[{"groupId":"BG000","value":"40"},{"groupId":"BG001","value":"23"},{"groupId":"BG002","value":"6"},{"groupId":"BG003","value":"69"}],"units":"Participants"}],"groups":[{"description":"pemetrexed, cisplatin and CBP501\n\npemetrexed, cisplatin and CBP501: CBP501 for injection is provided in single dose vials (20 mg) containing a sterile lyophilized powder comprising CBP501 peptide acetate salt (peptide base units). For administration, vial contents are reconstituted in 5% Dextrose Injection, USP, and added to a 100 mL IV bag of 5% Dextrose Injection, USP.\n\nPemetrexed: A commercial formulation of pemetrexed will be used, with reconstitution in 20mL 0.9% sodium chloride solution for injection, then dilution to 100mL.\n\nCisplatin: A commercial formulation will be used and will be diluted in 250 mL of normal saline for administration.","id":"BG000","title":"Pemetrexed, Cisplatin, and CBP501: Phase 2"},{"description":"pemetrexed and cisplatin\n\npemetrexed and cisplatin: Pemetrexed: A commercial formulation of pemetrexed will be used, with reconstitution in 20mL 0.9% sodium chloride solution for injection, then dilution to 100mL.\n\nCisplatin: A commercial formulation will be used and will be diluted in 250 mL of normal saline for administration.","id":"BG001","title":"Pemetrexed and Cisplatin: Phase 2"},{"description":"DL1: CBP501 16mg/m2, Alimta 500mg/m2, cisplatin 75mg/m2 DL2: CBP501 25mg/m2, Alimta 500mg/m2, cisplatin 75mg/m2","id":"BG002","title":"Pemetrexed, Cisplatin, and CBP501: Phase 1"},{"description":"Total of all reporting groups","id":"BG003","title":"Total"}],"measures":[{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","spread":"10.03","value":"63"},{"groupId":"BG001","spread":"12.10","value":"66.3"},{"groupId":"BG002","spread":"13.61","value":"62.8"},{"groupId":"BG003","spread":"10.86","value":"64.2"}]}]}],"dispersionType":"STANDARD_DEVIATION","paramType":"MEAN","title":"Age, Continuous","unitOfMeasure":"years"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"8"},{"groupId":"BG001","value":"3"},{"groupId":"BG002","value":"1"},{"groupId":"BG003","value":"12"}],"title":"Female"},{"measurements":[{"groupId":"BG000","value":"32"},{"groupId":"BG001","value":"20"},{"groupId":"BG002","value":"5"},{"groupId":"BG003","value":"57"}],"title":"Male"}]}],"paramType":"COUNT_OF_PARTICIPANTS","title":"Sex: Female, Male","unitOfMeasure":"Participants"}]}