{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"4"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"35"},{"groupId":"OG001","value":"33"}],"units":"Participants"}],"description":"Liquid chromatography tandem mass spectrometry (Quest Diagnostics). Persistently elevated serum estradiol level outside the post-menopausal range was defined as: Serum estradiol \\>10 pg/dl on two consecutive collections at least 4 weeks apart. 2. If baseline estradiol was \\>10 pg/dl, subsequent levels \\>10 pg/ml higher than baseline were considered a significant elevation outside the post-menopausal range.","groups":[{"description":"Estring 2mg ring inserted vaginally once every 12 weeks","id":"OG000","title":"Estring"},{"description":"Testosterone Cream 1% micronized in velvachol - 0.5 gm of cream vaginally each night for two weeks, then 3 times a week for total of 12 weeks of treatment","id":"OG001","title":"Testosterone Cream"}],"paramType":"NUMBER","populationDescription":"Per protocol, to be considered evaluable for the Primary Outcome, patients must complete both baseline evaluation and week 4 safety blood draw. 1 participant in the Testosterone arm was not evaluable.","reportingStatus":"POSTED","timeFrame":"12 Weeks","title":"Persistently Elevated Serum Estradiol Level Outside the Post-menopausal Range","type":"PRIMARY","unitOfMeasure":"participants"}