{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"3"},{"groupId":"OG001","value":"3"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"3"},{"groupId":"OG001","value":"3"}],"units":"Participants"}],"description":"An AE was defined as any untoward medical occurrence in a participant administered medicinal (investigational) product and that does not necessarily have a causal relationship with this product. An AE can therefore be any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease temporally associated with the use of a medicinal (investigational) product, whether or not related to the medicinal (investigational) product. See the adverse events section of the record for more details.","groups":[{"description":"Intravenous (IV) infusions of natalizumab 300 mg once every 28 days for 6 months.","id":"OG000","title":"Natalizumab 300 mg"},{"description":"Intravenous (IV) infusions of natalizumab 450 mg once every 28 days for 6 months.","id":"OG001","title":"Natalizumab 450 mg"}],"paramType":"NUMBER","reportingStatus":"POSTED","timeFrame":"Day 1 up to Month 6","title":"Number of Participants With Adverse Events (AEs)","type":"PRIMARY","unitOfMeasure":"participants"}