{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"265"}]}],"title":"Slow Metabolizers by Genotype"},{"categories":[{"measurements":[{"groupId":"OG000","value":"269"}]}],"title":"Fast Metabolizers by Genotype"}],"denoms":[{"counts":[{"groupId":"OG000","value":"534"}],"units":"Participants"}],"description":"Analyzed CYP2A6 by genotype. The variants present in people in the slow genotype group include \\*17, \\*20, \\*23,\\*27, \\*35, \\*9, \\*2, \\*25, \\*26, and \\*4. The fast metabolizers have none of the variant alleles tested.\n\nSlow metabolizers have any reduction or loss of function variant. Fast metabolizers are \\*1/\\*1 genotype by exclusion.","groups":[{"description":"All study participants were African American adults and received either bupropion (150mg bid) for 7 weeks in addition to health education counseling or placebo for 7 weeks in addition to health education counseling.","id":"OG000","title":"All Study Participants"}],"paramType":"COUNT_OF_PARTICIPANTS","populationDescription":"This variant is related to nicotine metabolism and was collected from all study participants but not analyzed by study arm as it does not relate to the study medication. Data pre-specified to be collected and reported as a single arm. Blood was unable to be analyzed for CYP2A6 genotype for 6 participants.","reportingStatus":"POSTED","timeFrame":"Week 0","title":"Number of Slow and Fast Metabolizers by Genotype","type":"SECONDARY","unitOfMeasure":"Participants"}