{"denomUnitsSelected":"Participants","description":"Neurological deterioration is defined as a decrease in WHO performance status as follows:\n\ndecrease in WHO performance status\n\n* for patients with baseline WHO performance status 0: deterioration to WHO performance status 2 or worse for which no other explanation is present, and which is maintained for at least three months\n* for patients with baseline WHO performance status 1 or 2: deterioration to WHO performance status 3 or worse for which no other explanation is present and which is maintained for at least three months\n\nThe date of neurological deterioration will be the first date the persistent decrease in performance status was diagnosed. Neurological deterioration free progression is the time interval between the date of randomization and the date of neurological deterioration or death whichever occurs first. If neither event has been observed, the patient is censored at the date of the last follow up examination","reportingStatus":"NOT_POSTED","timeFrame":"within 2 weeks of randomization; during radiotherapy at week 4 and 6; 4 weeks after the end of radiotherapy; Six monthly after the end of radiotherapy; Prior to each cycle of adjuvant therapy; Every six months after the documentation of first progression.","title":"Neurological Deterioration Free Survival","type":"SECONDARY"}