{"eventGroups":[{"description":"Fludarabine Busulfan chemotherapy regimen(Flu-Bu4), followed by allogeneic stem cell transplant from best available, matched donor.\n\nFludarabine/Busulfan x 4 days:\n\nFludarabine: 40 mg/m2/day in NS, administered IV over 30 minutes on days -5, -4, -3, and -2 pre-transplant.\n\nBusulfan: 3.2 mg/kg IV daily in NS over 4 hours on days -5, -4, -3, and -2.\n\nThe Fludarabine shall be administered prior to the Busulfan each day.","id":"EG000","otherNumAffected":20,"otherNumAtRisk":22,"seriousNumAffected":13,"seriousNumAtRisk":22,"title":"Flu-Bu4"}],"frequencyThreshold":"5","otherEvents":[{"organSystem":"Blood and lymphatic system disorders","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":22,"numEvents":2}],"term":"Blood/Bone Marrow - Other"},{"organSystem":"Blood and lymphatic system disorders","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":22,"numEvents":2}],"term":"Platelets"},{"organSystem":"Cardiac disorders","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":22,"numEvents":2}],"term":"Sinus bradycardia"},{"organSystem":"Cardiac disorders","stats":[{"groupId":"EG000","numAffected":8,"numAtRisk":22,"numEvents":9}],"term":"Sinus tachycardia"},{"organSystem":"Cardiac disorders","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":22,"numEvents":2}],"term":"Supraventricular extrasystoles"},{"organSystem":"Cardiac disorders","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":22,"numEvents":2}],"term":"Hypertension"},{"organSystem":"Cardiac disorders","stats":[{"groupId":"EG000","numAffected":6,"numAtRisk":22,"numEvents":6}],"term":"Hypotension"},{"organSystem":"General disorders","stats":[{"groupId":"EG000","numAffected":5,"numAtRisk":22,"numEvents":5}],"term":"Fatigue (asthenia, lethargy, malaise)"},{"organSystem":"General disorders","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":22,"numEvents":2}],"term":"Fever"},{"organSystem":"Psychiatric disorders","stats":[{"groupId":"EG000","numAffected":4,"numAtRisk":22,"numEvents":5}],"term":"Insomnia"},{"organSystem":"Metabolism and nutrition disorders","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":22,"numEvents":2}],"term":"Weight gain"},{"organSystem":"Skin and subcutaneous tissue disorders","stats":[{"groupId":"EG000","numAffected":6,"numAtRisk":22,"numEvents":8}],"term":"Dermatology/Skin - Other"},{"organSystem":"Skin and subcutaneous tissue disorders","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":22,"numEvents":2}],"term":"Pruritus/itching"},{"organSystem":"Skin and subcutaneous tissue disorders","stats":[{"groupId":"EG000","numAffected":6,"numAtRisk":22,"numEvents":8}],"term":"Rash/desquamation"},{"organSystem":"Gastrointestinal disorders","stats":[{"groupId":"EG000","numAffected":3,"numAtRisk":22,"numEvents":3}],"term":"Diarrhea"},{"organSystem":"Gastrointestinal disorders","stats":[{"groupId":"EG000","numAffected":4,"numAtRisk":22,"numEvents":4}],"term":"Dry mouth/salivary gland (xerostomia)"},{"organSystem":"Gastrointestinal disorders","stats":[{"groupId":"EG000","numAffected":3,"numAtRisk":22,"numEvents":3}],"term":"Gastrointestinal - Other (Specify)"},{"organSystem":"Gastrointestinal disorders","stats":[{"groupId":"EG000","numAffected":3,"numAtRisk":22,"numEvents":3}],"term":"Heartburn/dyspepsia"},{"organSystem":"Gastrointestinal disorders","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":22,"numEvents":2}],"term":"Incontinence, anal"},{"organSystem":"Gastrointestinal disorders","stats":[{"groupId":"EG000","numAffected":3,"numAtRisk":22,"numEvents":3}],"term":"Mucositis/stomatitis (clinical exam)"},{"organSystem":"Gastrointestinal disorders","stats":[{"groupId":"EG000","numAffected":6,"numAtRisk":22,"numEvents":7}],"term":"Taste alteration (dysgeusia)"},{"organSystem":"Gastrointestinal disorders","stats":[{"groupId":"EG000","numAffected":3,"numAtRisk":22,"numEvents":3}],"term":"Hemorrhage, GI"},{"organSystem":"Gastrointestinal disorders","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":22,"numEvents":2}],"term":"Hemorrhage, GI"},{"organSystem":"Renal and urinary disorders","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":22,"numEvents":3}],"term":"Hemorrhage, GU"},{"organSystem":"Renal and urinary disorders","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":22,"numEvents":2}],"term":"Hemorrhage, GU"},{"organSystem":"Respiratory, thoracic and mediastinal disorders","stats":[{"groupId":"EG000","numAffected":3,"numAtRisk":22,"numEvents":3}],"term":"Hemorrhage, pulmonary/upper respiratory"},{"organSystem":"Infections and infestations","stats":[{"groupId":"EG000","numAffected":5,"numAtRisk":22,"numEvents":5}],"term":"Infection - 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Other"},{"organSystem":"Renal and urinary disorders","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":22,"numEvents":2}],"term":"Renal failure"}]}