{"description":"At Risk for All-Cause Mortality includes all enrolled participants; at Risk for all other Adverse Events includes the safety population.\n\nA total of four chemotherapy regimen choices were allowed for the platinum-doublet treatment, and chemotherapy regimen choice was at the discretion of the treating physician and was made prior to randomization. The trial did not intent to look at the four chemotherapy regimens separately in terms of safety and efficacy.","eventGroups":[{"deathsNumAffected":182,"deathsNumAtRisk":200,"description":"ARM A: Patients receive one of the four chemotherapy regimens\n\nARM IA: Patients receive chemotherapy comprising docetaxel intravenously (IV) over 1 hour and cisplatin IV over 1-2 hours on day 1. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.\n\nARM IIA: Patients receive docetaxel IV over 1 hour and carboplatin IV over 30 minutes on day 1. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.\n\nARM IIIA: Patients receive cisplatin IV over 1-2 hours on day 1 and fluorouracil IV continuously on days 1-4. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.\n\nARM IVA: Patients receive carboplatin IV over 30 minutes on day 1 and fluorouracil IV continuously on days 1-4. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.","id":"EG000","otherNumAffected":50,"otherNumAtRisk":199,"seriousNumAffected":135,"seriousNumAtRisk":199,"title":"Chemotherapy (Arm A)"},{"deathsNumAffected":175,"deathsNumAtRisk":203,"description":"ARM B: Patients receive bevacizumab in addition to the chemotherapy regimen as in arm A\n\nARM IB: Patients receive bevacizumab IV over 30-90 minutes on day 1 and docetaxel and cisplatin as in Arm IA.\n\nARM IIB: Patients receive bevacizumab as in arm IB and docetaxel and carboplatin as in Arm IIA.\n\nARM IIIB: Patients receive bevacizumab as in Arm IB and cisplatin and fluorouracil as in Arm IIIA.\n\nARM IVB: Patients receive bevacizumab as in Arm IB and carboplatin and fluorouracil as in Arm IVA.","id":"EG001","otherNumAffected":50,"otherNumAtRisk":193,"seriousNumAffected":162,"seriousNumAtRisk":193,"title":"Chemotherapy + Bevacizumab (Arm 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