{"analyses":[{"ciNumSides":"TWO_SIDED","groupIds":["OG000","OG001","OG002"],"nonInferiorityComment":"The study was designed as a standard dose-escalation study, dose-finding pilot study. The primary outcome measures were safety (hypercalcemia, hypophosphatemia and symptoms/hemodynamic measurements). A modified Fibronacci dose-escalation scheme was employed.","nonInferiorityType":"NON_INFERIORITY_OR_EQUIVALENCE","pValue":"0.61","pValueComment":"The reported p-value corresponds to all Arms/Groups at all time points compared to baseline","statisticalComment":"The level of statistical significance was set at .05 (two-tailed)","statisticalMethod":"Mixed Models Analysis","testedNonInferiority":true}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.26","value":"3.43"},{"groupId":"OG001","spread":"0.23","value":"3.91"},{"groupId":"OG002","spread":"0.35","value":"3.38"}]}],"title":"Baseline"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.20","value":"4.48"},{"groupId":"OG001","spread":"0.23","value":"4.08"},{"groupId":"OG002","spread":"0.46","value":"3.47"}]}],"title":"Day 2"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.30","value":"4.28"},{"groupId":"OG001","spread":"0.26","value":"3.74"},{"groupId":"OG002","spread":"0.50","value":"3.25"}]}],"title":"Day 3"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.31","value":"4.42"},{"groupId":"OG001","spread":"0.31","value":"3.75"},{"groupId":"OG002","spread":"0.45","value":"3.15"}]}],"title":"Day 4"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.02","value":"4.43"},{"groupId":"OG001","spread":"0.34","value":"3.95"},{"groupId":"OG002","spread":"0.45","value":"3.37"}]}],"title":"Day 5"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.08","value":"4.90"},{"groupId":"OG001","spread":"0.11","value":"3.98"},{"groupId":"OG002","spread":"0.35","value":"3.38"}]}],"title":"Day 6"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.08","value":"4.15"},{"groupId":"OG001","spread":"0.19","value":"3.98"},{"groupId":"OG002","spread":"0.28","value":"2.95"}]}],"title":"Day 7"}],"denoms":[{"counts":[{"groupId":"OG000","value":"3"},{"groupId":"OG001","value":"6"},{"groupId":"OG002","value":"3"},{"groupId":"OG003","value":"0"}],"units":"Participants"}],"description":"mg/dl calculated from daily second morning void","dispersionType":"Standard Error","groups":[{"description":"PTHrP(1-36) 2 picomoles/kg/hr for one week.","id":"OG000","title":"Group 1"},{"description":"PTHrP(1-36) 4 picomoles/kg/hr for one week","id":"OG001","title":"Group 2"},{"description":"PTHrP(1-36) 5 picomoles/kg/hr for one week","id":"OG002","title":"Group 3"},{"description":"PTHrP(1-36) 6 picomoles/kg/hr for one week","id":"OG003","title":"Group 4"}],"paramType":"MEAN","reportingStatus":"POSTED","timeFrame":"daily","title":"Tubular Maximum of Phosphorous (TmP/GFR)","type":"SECONDARY","unitOfMeasure":"mg/dl"}