{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"11"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"35"}],"units":"Participants"}],"description":"Organ response was evaluated on the basis of improvement of one or more affected organ; only one parameter was required to satisfy the criteria. Response needed to be maintained for a minimum of 3 months to be considered valid.\n\nRenal response required a 50% reduction in 24-hour urine protein excretion (at least 0.5 g/d) with stable creatinine. Cardiac response required one of \\>= 2-mm reduction in the interventricular septal (IVS) thickness by echocardiogram, or improvement of ejection fraction by \\>= 20%, or improvement by 2 NYHA classes without an increase in diuretic use. Hepatic response required either \\>= 50% decrease in (or normalization of) an initially elevated alkaline phosphatase level or reduction in the size of the liver by at least 2 cm by radiographic determination. Gastrointestinal tract improvement was defined as normalization of a low serum carotene level, or reduction of diarrhea to \\< 50% of previous movements/day, or decrease in fecal fat excretion by 50%.","groups":[{"description":"Lenalidomide (Len) 15mg daily (days 1-21); Cyclophosphamide (Cyc) 300 mg/m\\^2 (days 1, 8, 15); Dexamethasone (Dex) 40 mg weekly","id":"OG000","title":"Len/Cyc/Dex"}],"paramType":"NUMBER","reportingStatus":"POSTED","timeFrame":"Duration of study (up to 3 years)","title":"Number of Patients With Organ Response","type":"SECONDARY","unitOfMeasure":"participants"}