{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"41.9"},{"groupId":"OG001","value":"18.8"}]}],"title":"Dose Increase(s) only"},{"categories":[{"measurements":[{"groupId":"OG000","value":"8.6"},{"groupId":"OG001","value":"19.6"}]}],"title":"Dose Decrease(s) only"},{"categories":[{"measurements":[{"groupId":"OG000","value":"11.4"},{"groupId":"OG001","value":"18.8"}]}],"title":"Dose Decrease(s) and Increase(s)"},{"categories":[{"measurements":[{"groupId":"OG000","value":"38.1"},{"groupId":"OG001","value":"42.9"}]}],"title":"No Dose Change"}],"denoms":[{"counts":[{"groupId":"OG000","value":"105"},{"groupId":"OG001","value":"112"}],"units":"Participants"}],"description":"The total number of dose adjustments needed to achieve stabilized response was calculated from Day 1 until the first 8-week time window in which response was achieved. A participant was defined as having achieved a stable Hb response, if at least 75% of the scheduled Hb values were between 10.0 g/dL and 12.0 g/dL and \\>=1.0 g/dL from baseline for any 8-week time period, regardless of the requirement for dose adjustment for Hb maintenance. Achievement of stable response was determined using a moving 8-week time window, moving forward by 14 days in each iteration starting at Day 15, searching to see if the following conditions were met: 1) At least 3 scheduled Hb values (75% of the scheduled Hb values) in any 8-week time window were \\>=1.0 g/dL from baseline (as calculated above) and within the range of 10.0 g/dL to 12.0 g/dL. 2) There were at least 3 recorded Hb values within the time window.","groups":[{"description":"Participants received Mircera (Methoxy polyethylene glycol-epoetin beta), administered SC at a starting dose of 1.2 mcg/kg once every 4 weeks for 28 weeks.","id":"OG000","title":"Mircera"},{"description":"Participants received darbepoetin alfa, administered SC once weekly or once every 2 weeks according to local labeling specifications for 28 weeks.","id":"OG001","title":"Darbepoetin Alfa"}],"paramType":"NUMBER","populationDescription":"ITT population. Here, N=number of participants analyzed for this measure.","reportingStatus":"POSTED","timeFrame":"Baseline to Week 28","title":"Percentage of Participants Who Required Dose Adjustments to Achieve a Stabilized Response","type":"SECONDARY","unitOfMeasure":"percentage of participants"}