{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"0","value":"0"},{"groupId":"OG001","spread":"49.7","value":"808"},{"groupId":"OG002","spread":"273.3","value":"16593"},{"groupId":"OG003","spread":"61.5","value":"161811"},{"groupId":"OG004","spread":"0","value":"596308"},{"groupId":"OG005","spread":"60.7","value":"4331537"},{"groupId":"OG006","spread":"41.7","value":"9292602"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"2"},{"groupId":"OG001","value":"3"},{"groupId":"OG002","value":"3"},{"groupId":"OG003","value":"5"},{"groupId":"OG004","value":"2"},{"groupId":"OG005","value":"3"},{"groupId":"OG006","value":"10"}],"units":"Participants"}],"description":"AUC(INF), area under the plasma concentration-time curve from zero to the last time of the last quantifiable concentration within the dosing interval was calculated for Cycle 1.","dispersionType":"Geometric Coefficient of Variation","groups":[{"description":"IV bolus injection","id":"OG000","title":"IPH2101 0.0003 mg/kg"},{"description":"IV bolus injection","id":"OG001","title":"IPH2101 0.003 mg/kg"},{"description":"IV bolus injection","id":"OG002","title":"IPH2101 0.015 mg/kg"},{"description":"IV 1 hour infusion","id":"OG003","title":"IPH2101 0.075 mg/kg"},{"description":"IV 1 hour infusion","id":"OG004","title":"IPH2101 0.3mg/kg"},{"description":"IV 1 hour infusion","id":"OG005","title":"IPH2101 1 mg/kg"},{"description":"IV 1 hour infusion","id":"OG006","title":"IPH2101 3 mg/kg"}],"paramType":"GEOMETRIC_MEAN","reportingStatus":"POSTED","timeFrame":"Anti-KIR (1-7F9) concentrations were measured prior to infusion at 0.167, 1, 3, 6, 12 and 24 hours and then on Days 7, 14 and 21 after the start of the first dose administration","title":"Area Under the Plasma-concentration-time Curve [AUC (INF)] of IPH2101 After Cycle 1 Administration","type":"SECONDARY","unitOfMeasure":"ng*hours/ml"}